Perceptual characteristics of Parkinsonian speech: a comparison of the pharmacological effects of levodopa across speech and non-speech motor systems.
The purpose of this study was to: (1) define perceptual speech characteristics of idiopathic Parkinson disease (IPD) across 35 speech dimensions adapted from Darley et al. [19] and grouped under six speech-sign clusters (respiration, phonation, resonance, articulation, prosody and rate); (2) examine...
| Publicado en: | NeuroRehabilitation Vol. 24; no. 2; pp. 131 - 145 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105525043&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105525043 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10538135 3RE jtl: NeuroRehabilitation issn: 10538135 maglogo: N pubinfo: dt: 2009 vid: 24 iid: 2 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 105525043 2010275738 10.3233/NRE-2009-0462 NLM19339752 105525043 ppf: 131 ppct: 14 formats: fmt: @attributes: type: P tig: atl: Perceptual characteristics of Parkinsonian speech: a comparison of the pharmacological effects of levodopa across speech and non-speech motor systems. aug: au: Plowman-Prine EK Okun MS Sapienza CM Shrivastav R Fernandez HH Foote KD Ellis C Rodriguez AD Burkhead LM Rosenbek JC affil: Department of Neurology, University of Florida, Gainesville, FL 32610, USA. emily.prine@neurology.ufl.edu sug: subj: Levodopa Therapeutic Use Parkinson Disease Complications Parkinson Disease Drug Therapy Speech Disorders Physiopathology Aged Case Studies Coefficient alpha Female Interrater Reliability Intraclass Correlation Coefficient Intrarater Reliability Male Middle Age Parkinson Disease Physiopathology Post Hoc Analysis Scales Wilcoxon Signed Rank Test Human Aged: 65+ years Middle Aged: 45-64 years Female Male ab: The purpose of this study was to: (1) define perceptual speech characteristics of idiopathic Parkinson disease (IPD) across 35 speech dimensions adapted from Darley et al. [19] and grouped under six speech-sign clusters (respiration, phonation, resonance, articulation, prosody and rate); (2) examine the effects of levodopa on the 35 perceptual speech dimensions and speech-sign clusters; and (3) to compare the relative effectiveness of levodopa on global motor functioning vs. speech production. Sixteen patients with IPD read the 'Grandfather Passage' both 'on' and 'off' levodopa. Three blinded speech-language pathologists performed perceptual speech analyses using a seven-point scale. The diagnosis of IPD was made by a movement disorders fellowship trained neurologist who applied UK Brain bank criteria and administered the Unified Parkinson Disease Rating Scale. Concordant with previous studies, the results of this experiment indicated that IPD disrupted multiple speech production subsystems, with prosody being the most severely affected domain. The perceptual dimensions that were most severely affected included: (1) sound imprecision; (2) mono-loudness; (3) mono-pitch; (4) reduced stress and (5) harsh voice. No significant differences were obtained between medicated states ('on'/'off') for any of the 35 individual speech dimensions and speech-sign clusters. Global motor function significantly improved following dopaminergic medications. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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