Curcumin suppresses the paclitaxel-induced nuclear factor-[kappa]B in breast cancer cells and potentiates the growth inhibitory effect of paclitaxel in a breast cancer nude mice model.
Most anticancer agents activate nuclear factor kappa B (NF-kappaB), which can mediate cell survival, proliferation, and metastasis. Curcumin has been shown to inhibit the growth of various cancer cells, without toxicity to normal cells. The antitumor effects of curcumin could be due in part to the i...
| Published in: | Breast Journal Vol. 15; no. 3; pp. 223 - 230 |
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| Main Authors: | , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
May/Jun2009
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| Online Access: | View this record in EBSCOhost |