Dual-energy CT for the characterization of urinary calculi: In vitro and in vivo evaluation of a low-dose scanning protocol.

The efficiency and radiation dose of a low-dose dual-energy (DE) CT protocol for the evaluation of urinary calculus disease were evaluated. A low-dose dual-source DE-CT renal calculi protocol (140 kV, 46 mAs; 80 kV, 210 mAs) was derived from the single-energy (SE) CT protocol used in our institution...

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Published in:European Radiology Vol. 19; no. 6; pp. 1553 - 1560
Main Authors: Thomas C, Patschan O, Ketelsen D, Tsiflikas I, Reimann A, Brodoefel H, Buchgeister M, Nagele U, Stenzl A, Claussen C, Kopp A, Heuschmid M, Schlemmer HP, Thomas, C, Patschan, O, Ketelsen, D, Tsiflikas, I, Reimann, A, Brodoefel, H, Buchgeister, M
Format: research Journal Article
Published: Springer Nature Jun2009
Online Access:View this record in EBSCOhost
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      dt: Jun2009
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      pub: Springer Nature
      place: New York, New York
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        atl: Dual-energy CT for the characterization of urinary calculi: In vitro and in vivo evaluation of a low-dose scanning protocol.
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          Thomas C
          Patschan O
          Ketelsen D
          Tsiflikas I
          Reimann A
          Brodoefel H
          Buchgeister M
          Nagele U
          Stenzl A
          Claussen C
          Kopp A
          Heuschmid M
          Schlemmer HP
          Thomas, C
          Patschan, O
          Ketelsen, D
          Tsiflikas, I
          Reimann, A
          Brodoefel, H
          Buchgeister, M
        affil: Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany
      sug:
        subj:
          Absorptiometry, Photon Methods
          Tomography, X-Ray Computed Methods
          Urinary Calculi Radiography
          Female
          Male
          Radiation Dosage
          Reproducibility of Results
          Sensitivity and Specificity
          Human
          Female
          Male
      ab: The efficiency and radiation dose of a low-dose dual-energy (DE) CT protocol for the evaluation of urinary calculus disease were evaluated. A low-dose dual-source DE-CT renal calculi protocol (140 kV, 46 mAs; 80 kV, 210 mAs) was derived from the single-energy (SE) CT protocol used in our institution for the detection of renal calculi (120 kV, 75 mAs). An Alderson-Rando phantom was equipped with thermoluminescence dosimeters and examined by CT with both protocols. The effective doses were calculated. Fifty-one patients with suspected or known urinary calculus disease underwent DE-CT. DE analysis was performed if calculi were detected using a dedicated software tool. Results were compared to chemical analysis after invasive calculus extraction. An effective dose of 3.43 mSv (male) and 5.30 mSv (female) was measured in the phantom for the DE protocol (vs. 3.17/4.57 mSv for the SE protocol). Urinary calculi were found in 34 patients; in 28 patients, calculi were removed and analyzed (23 patients with calcified calculi, three with uric acid calculi, one with 2,8-dihyxdroxyadenine-calculi, one patient with a mixed struvite calculus). DE analysis was able to distinguish between calcified and non-calcified calculi in all cases. In conclusion, dual-energy urinary calculus analysis is effective also with a low-dose protocol. The protocol tested in this study reliably identified calcified urinary calculi in vivo.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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