Status of psychological trials in breast cancer patients: a report of three meta-analyses.
This systematic review reports the results of three meta-analyses addressing the clinical efficacy of psychological interventions in breast cancer patients. Three outcome variables were examined: anxiety, depression and quality of life. Several moderator variables were found to both account for inte...
| Publicado en: | Psychiatry: Interpersonal & Biological Processes Vol. 72; no. 1; pp. 50 - 70 |
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| Autores principales: | , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Spring2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105532659&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105532659 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00332747 PST jtl: Psychiatry: Interpersonal & Biological Processes issn: 00332747 maglogo: N pubinfo: dt: Spring2009 vid: 72 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 105532659 2010282666 10.1521/psyc.2009.72.1.50 NLM19366294 105532659 ppf: 50 ppct: 20 formats: fmt: @attributes: type: P tig: atl: Status of psychological trials in breast cancer patients: a report of three meta-analyses. aug: au: Naaman SC Radwan K Fergusson D Johnson S affil: Faculty of Medicine, University of Ottawa, Ontario, Canada; snaaman@ottawaheart.ca sug: subj: Breast Neoplasms Therapy Cancer Patients Outcome Assessment Psychotherapy, Group Anxiety CINAHL Database Coding Confidence Intervals Data Analysis, Statistical Depression Effect Size Embase Female Medline Meta Analysis Psycinfo Quality of Life Scales Human Female ab: This systematic review reports the results of three meta-analyses addressing the clinical efficacy of psychological interventions in breast cancer patients. Three outcome variables were examined: anxiety, depression and quality of life. Several moderator variables were found to both account for inter-trial heterogeneity and interact with treatment efficacy; methodological quality, prognosis, treatment type, orientation and duration. A clinically moderate treatment effect was found for anxiety (-0.40, 95% CI, -0.72 to -0.08, N = 1278). This was not robust to study quality, but remained stable for patients with more advanced disease. Short-term group therapy was more effective than longer term intervention and individual ones. A clinically moderate-to-strong effect was found in trials assessing depression (-1.01, 95% CI, -1.48 to -0.54, N = 1324). A more robust finding of -0.47 (95% -0.69 to -0.24) was based on methodologically more reliable studies treating patients with high psychological morbidity. Intervention was shown to have moderate effects on improving QOL (0.74, 95% CI, 0.12 to 1.37, N = 623), though it was not robust to study quality. Findings suggest that short-term treatments with a focus on coping may be more suitable for early breast cancer patients. Patients with advanced breast disease appear to benefit more from longer term interventions which emphasize support. Recommendations are also made for future clinical trials. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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