Prediction of postpartum depression using multilayer perceptrons and pruning.

Objective: The main goal of this paper is to obtain a classification model based on feed-forward multilayer perceptrons in order to improve postpartum depression prediction during the 32 weeks after childbirth with a high sensitivity and specificity and to develop a tool to be integrated in a decisi...

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Published in:Methods of Information in Medicine Vol. 48; no. 3; pp. 291 - 299
Main Authors: Tortajada S, García-Gomez JM, Vicente J, Sanjuán J, de Frutos R, Martín-Santos R, García-Esteve L, Gornemann I, Gutiérrez-Zotes A, Canellas F, Carracedo A, Gratacos M, Guillamat R, Baca-García E, Robles M, Tortajada, Salvador, García-Gomez, Juan M, Vicente, Javier, Sanjuán, Julio, de Frutos, Rosa
Format: research Journal Article
Published: Thieme Medical Publishing Inc. 2009
Online Access:View this record in EBSCOhost
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      dt: 2009
      vid: 48
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      pub: Thieme Medical Publishing Inc.
      place: New York, New York
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        10.3414/ME0562
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        atl: Prediction of postpartum depression using multilayer perceptrons and pruning.
      aug:
        au:
          Tortajada S
          García-Gomez JM
          Vicente J
          Sanjuán J
          de Frutos R
          Martín-Santos R
          García-Esteve L
          Gornemann I
          Gutiérrez-Zotes A
          Canellas F
          Carracedo A
          Gratacos M
          Guillamat R
          Baca-García E
          Robles M
          Tortajada, Salvador
          García-Gomez, Juan M
          Vicente, Javier
          Sanjuán, Julio
          de Frutos, Rosa
        affil: IBIME, Instituto de Aplicaciones de las Tecnologías de la Información y de las Comunicaciones Avanzadas (ITACA), Universidad Politécnica de Valencia, Valencia, Spain
      sug:
        subj:
          Depression, Postpartum Diagnosis
          Multilayer Perceptrons
          Adult
          Algorithms
          Female
          Forecasting
          Logistic Regression
          Nervous System
          Prospective Studies
          Spain
          Human
          Adult: 19-44 years
          Female
      ab: Objective: The main goal of this paper is to obtain a classification model based on feed-forward multilayer perceptrons in order to improve postpartum depression prediction during the 32 weeks after childbirth with a high sensitivity and specificity and to develop a tool to be integrated in a decision support system for clinicians.Materials and Methods: Multilayer perceptrons were trained on data from 1397 women who had just given birth, from seven Spanish general hospitals, including clinical, environmental and genetic variables. A prospective cohort study was made just after delivery, at 8 weeks and at 32 weeks after delivery. The models were evaluated with the geometric mean of accuracies using a hold-out strategy.Results: Multilayer perceptrons showed good performance (high sensitivity and specificity) as predictive models for postpartum depression.Conclusions: The use of these models in a decision support system can be clinically evaluated in future work. The analysis of the models by pruning leads to a qualitative interpretation of the influence of each variable in the interest of clinical protocols.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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