Estimation of distribution algorithms as logistic regression regularizers of microarray classifiers.

Objectives: The "large k (genes), small N (samples)" phenomenon complicates the problem of microarray classification with logistic regression. The indeterminacy of the maximum likelihood solutions, multicollinearity of predictor variables and data over-fitting cause unstable parameter estimates. Mor...

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Bibliographic Details

Published in:	Methods of Information in Medicine Vol. 48; no. 3; pp. 236 - 242
Main Authors:	Bielza C, Robles V, Larranaga P, Bielza, Concha, Robles, V, Larranaga, P
Format:	research Journal Article
Published:	Thieme Medical Publishing Inc. 2009
Online Access:	View this record in EBSCOhost