Treatment satisfaction with insulin glargine in patients with diabetes mellitus in a university hospital clinic in Sweden.

Background: Few studies evaluate patients' perspectives when a new drug is introduced to treat chronic diseases such as diabetes mellitus. The clinical role of a new insulin treatment, in terms of the relationship between higher cost and better treatment outcomes (as defined from the patient perspec...

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Publicado en:European Diabetes Nursing Vol. 6; no. 1; pp. 17 - 23
Autores principales: Gershater MA, Frid A, Apelqvist J
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Spring2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Spring2009
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        2010301666
        10.1002/edn.127
        105544342
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        atl: Treatment satisfaction with insulin glargine in patients with diabetes mellitus in a university hospital clinic in Sweden.
      aug:
        au:
          Gershater MA
          Frid A
          Apelqvist J
        affil: Department of Endocrinology, Malmö University Hospital, Malmö, Sweden
      sug:
        subj:
          Diabetes Mellitus Drug Therapy
          Glycated Hemoglobin Blood
          Hypoglycemia
          Insulin Administration and Dosage
          Patient Satisfaction
          Data Analysis Software
          Decision Making, Clinical
          Demography
          Descriptive Statistics
          Female
          Male
          Medical Records
          Questionnaires
          Record Review
          Summated Rating Scaling
          Surveys
          Sweden
          Human
          Female
          Male
      ab: Background: Few studies evaluate patients' perspectives when a new drug is introduced to treat chronic diseases such as diabetes mellitus. The clinical role of a new insulin treatment, in terms of the relationship between higher cost and better treatment outcomes (as defined from the patient perspective) has been discussed. We sought to explore patient satisfaction with a new insulin treatment (insulin glargine). At its launch in 2002/3 it was purported to provide constant, peakless insulin release following once- or twice-daily administration, thus leading to fewer hypoglycaemic episodes while providing metabolic control equivalent to that achieved with NPH human basal insulin. Aims: To investigate the indications used for prescription of a new drug and its clinical effects on glycosylated haemoglobin (HbA1c) levels, perceived hypoglycaemic events and patient satisfaction. Methods: The Diabetes Treatment Satisfaction Questionnaire (Status Version, DTSQ-s), which measures satisfaction with treatment regimen, and perceived frequency of hyperglycaemia and hypoglycemia, was circulated to all living patients who had ever started treatment with insulin glargine at the Department of Endocrinology at Malmö University Hospital. Medical records of 913 patients were assessed for HbA1c levels at 0 and 12 months after starting insulin glargine therapy. Results: Completed questionnaires were returned by 615 of 960 patients (64%) who had ever started insulin glargine. The main indications for starting treatment were physicians' or nurses' initiatives, desire for fewer fluctuations and improved metabolic control. HbA1c levels fell by 0.41% for patients with type 1 diabetes and by 0.68% for those with type 2 diabetes. The mean DTSQ-s score was 28.45 for satisfaction, whereas the mean perceived hypoglycaemic/hyperglycaemic events score was 3. Conclusion: Treatment satisfaction was very high and perceived frequency of hypoglycaemia/hyperglycaemia was very low. The indications for treatment of insulin glargine are being followed in accordance with national recommendations.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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