Chronic urticaria and Helicobacter pylori.
Background: Helicobacter pylori (HP) have recently emerged as a novel eliciting factor for chronic urticaria (CU). The possible association between HP and CU has enormous potential, as eradicating HP could cure CU.Aims and Objectives: We conducted a study to assess the prevalence of HP infection and...
| Publicado en: | Indian Journal of Medical Sciences Vol. 62; no. 4; pp. 157 - 163 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Scientific Scholar LLC
Apr2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105546429&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105546429 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00195359 SV7 jtl: Indian Journal of Medical Sciences issn: 00195359 maglogo: N pubinfo: dt: Apr2008 vid: 62 iid: 4 pid: 56013 pub: Scientific Scholar LLC place: Pittsford, New York artinfo: ui: 105546429 NLM18445982 2009917337 10.4103/0019-5359.40579 NLM18445982 105546429 ppf: 157 ppct: 6 formats: tig: atl: Chronic urticaria and Helicobacter pylori. aug: au: Yadav MK Rishi JP Nijawan S Yadav, Mukesh K Rishi, Jai P Nijawan, S affil: Department of Medicine, SMS Medical College, Jaipur, India sug: subj: Helicobacter Infections Epidemiology Helicobacter Pylori Urticaria Epidemiology Adolescence Adult Amoxicillin Therapeutic Use Case Control Studies Chronic Disease Comorbidity Drug Therapy, Combination Female Helicobacter Infections Drug Therapy Helicobacter Infections Microbiology Incidence India Male Metronidazole Therapeutic Use Middle Age Omeprazole Therapeutic Use Quality of Life Questionnaires Treatment Outcomes Urticaria Drug Therapy Urticaria Microbiology Human Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Background: Helicobacter pylori (HP) have recently emerged as a novel eliciting factor for chronic urticaria (CU). The possible association between HP and CU has enormous potential, as eradicating HP could cure CU.Aims and Objectives: We conducted a study to assess the prevalence of HP infection and effect of bacterium eradication on skin lesions in patients of chronic idiopathic urticaria (CIU).Settings and Design: Four hundred sixty patients of CU attending the allergy clinic, SMS hospital, Jaipur during the period February 6, 2004, to February 6, 2006, were screened for possible eliciting factors. Patients with CIU were enrolled and others were excluded.Materials and Methods: Sixty-eight patients of CIU and similar number of age and sex matched controls, attending the allergy clinic, SMS Hospital, Jaipur were enrolled in the study. All patients underwent endoscopy with antral biopsy for urease and histopathology to identify HP-associated gastritis. Infected patients were given HP eradication therapy. Eradication of bacterium was confirmed by fecal antigen assay. Subjective response to treatment was judged using chronic urticaria quality-of-life questionnaire (CU-Q 2 oL) while objective response to treatment was judged by need for 'rescue medication' (antihistaminics).Statistical Analysis: Data were analyzed using Chi square and paired 't' test for their level of significance.Results: HP associated gastritis was present in 48 (70.58%) patients, out of which 39 (81.25%) patients responded to eradication therapy. Ten (50.00%) patients without HP associated gastritis showed response to symptomatic therapy. Overall 49 (72.05%) patients responded and 19 (27.94%) showed no response. The value of chi2 was 28.571 (P = 0.003), which showed significant association between presence of HP and response to eradication regimen.Conclusion: The response of HP eradication therapy in infected patients of CIU is significant. HP should be included in diagnostic workup of patients with CIU. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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