Computer-aided detection of pulmonary embolism: influence on radiologists' detection performance with respect to vessel segments.

The purpose was to assess the sensitivity of a CAD software prototype for the detection of pulmonary embolism in MDCT chest examinations with regard to vessel level and to assess the influence on radiologists' detection performance. Forty-three patients with suspected PE were included in this retros...

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Published in:European Radiology Vol. 18; no. 7; pp. 1350 - 1356
Main Authors: Das M, Mühlenbruch G, Helm A, Bakai A, Salganicoff M, Stanzel S, Liang J, Wolf M, Günther RW, Wildberger JE, Das, Marco, Mühlenbruch, Georg, Helm, Anita, Bakai, Annemarie, Salganicoff, Marcos, Stanzel, Sven, Liang, Jianming, Wolf, Matthias, Günther, Rolf W, Wildberger, Joachim Ernst
Format: research Journal Article
Published: Springer Nature Jul2008
Online Access:View this record in EBSCOhost
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        atl: Computer-aided detection of pulmonary embolism: influence on radiologists' detection performance with respect to vessel segments.
      aug:
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          Das M
          Mühlenbruch G
          Helm A
          Bakai A
          Salganicoff M
          Stanzel S
          Liang J
          Wolf M
          Günther RW
          Wildberger JE
          Das, Marco
          Mühlenbruch, Georg
          Helm, Anita
          Bakai, Annemarie
          Salganicoff, Marcos
          Stanzel, Sven
          Liang, Jianming
          Wolf, Matthias
          Günther, Rolf W
          Wildberger, Joachim Ernst
        affil: Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstr. 30, 52072 Aachen, Germany
      sug:
        subj:
          Clinical Competence
          Pulmonary Embolism Radiography
          Radiographic Image Interpretation, Computer-Assisted
          Tomography, X-Ray Computed Methods
          Contrast Media
          Female
          Growth Substances Diagnostic Use
          Growth Substances
          Male
          Middle Age
          Sensitivity and Specificity
          Human
          Middle Aged: 45-64 years
          Female
          Male
      ab: The purpose was to assess the sensitivity of a CAD software prototype for the detection of pulmonary embolism in MDCT chest examinations with regard to vessel level and to assess the influence on radiologists' detection performance. Forty-three patients with suspected PE were included in this retrospective study. MDCT chest examinations with a standard PE protocol were acquired at a 16-slice MDCT. All patient data were read by three radiologists (R1, R2, R3), and all thrombi were marked. A CAD prototype software was applied to all datasets, and each finding of the software was analyzed with regard to vessel level. The standard of reference was assessed in a consensus read. Sensitivity for the radiologists and CAD software was assessed. Thirty-three patients were positive for PE, with a total of 215 thrombi. The mean overall sensitivity for the CAD software alone was 83% (specificity, 80%). Radiologist sensitivity was 77% = R3, 82% = R2, and R1 = 87%. With the aid of the CAD software, sensitivities increased to 98% (R1), 93% (R2), and 92% (R3) (p<0.0001). CAD performance at the lobar level was 87%, at the segmental 90% and at the subsegmental 77%. With the use of CAD for PE, the detection performance of radiologists can be improved.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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