Camptocormia and Parkinson's disease: MR imaging.
Camptocormia is characterized by an excessive anterior flexion of the spine that appears only when standing or walking. The origin of this symptom remains unknown, but recent clinical reports of camptocormia associated with Parkinson's disease (PD) suggest cerebral involvement in the pathogenesis of...
| Publicado en: | European Radiology Vol. 18; no. 8; pp. 1710 - 1720 |
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| Autores principales: | , , , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105551833&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105551833 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Aug2008 vid: 18 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105551833 32987512 NLM18351343 2010023542 10.1007/s00330-008-0927-8 NLM18351343 105551833 ppf: 1710 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Camptocormia and Parkinson's disease: MR imaging. aug: au: Bonneville F Bloch F Kurys E du Montcel ST Welter ML Bonnet AM Agid Y Dormont D Houeto JL Bonneville, Fabrice Bloch, Frédéric Kurys, Ewa du Montcel, Sophie Tezenas Welter, Marie-Laure Bonnet, Anne-Marie Agid, Yves Dormont, Didier Houeto, Jean-Luc affil: Service de Neuroradiologie, Hôpital de la Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47 Boulevard de l'Hôpital, 75651, Paris Cedex 13, France sug: subj: Brain Pathology Magnetic Resonance Imaging Parkinson Disease Complications Parkinson Disease Pathology Spinal Curvatures Complications Spinal Curvatures Pathology Aged Atrophy Pathology Body Weights and Measures Male Human Aged: 65+ years Male ab: Camptocormia is characterized by an excessive anterior flexion of the spine that appears only when standing or walking. The origin of this symptom remains unknown, but recent clinical reports of camptocormia associated with Parkinson's disease (PD) suggest cerebral involvement in the pathogenesis of camptocormia. This study was undertaken to investigate the hypothesis that camptocormia in PD has a central origin. Seventeen PD patients with camptocormia were prospectively enrolled and were compared to 10 matched PD patients without camptocormia and 12 normal controls. The normalized volumes of the brain, striatal nuclei, and the cross-sectional areas of the midbrain and pons were measured on three-dimensional magnetic resonance imaging. Data were correlated with the severity of the symptoms. The normalized axial surface of the midbrain was statistically smaller in PD patients with camptocormia than in normal controls (P = 0.01). The normalized volumetric data were not statistically different in PD patients with camptocormia. There was a significant negative correlation between the severity of camptocormia and the normalized brain volume (P < 0.009; R = -0.649) and sagittal pons area (P < 0.01; R = -0.642). The results suggest that PD with camptocormia may represent a selective form of PD in which a specific neuronal dysfunction possibly occurs within the brainstem. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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