Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma.

The aim was to compare the performances of contrast-enhanced (CE) ultrasonography (US) and spiral computed tomography (CT) in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma (HCC). We studied 50 patients with HCC who had biopsy-proven portal vein th...

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Publicado en:European Radiology Vol. 18; no. 8; pp. 1749 - 1757
Autores principales: Rossi S, Ghittoni G, Ravetta V, Torello Viera F, Rosa L, Serassi M, Scabini M, Vercelli A, Tinelli C, Dal Bello B, Burns PN, Calliada F, Rossi, Sandro, Ghittoni, Giorgia, Ravetta, Valentina, Torello Viera, Francesca, Rosa, Laura, Serassi, Martina, Scabini, Mara, Vercelli, Alessandro
Formato: research Journal Article
Publicado: Springer Nature Aug2008
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma.
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          Rossi S
          Ghittoni G
          Ravetta V
          Torello Viera F
          Rosa L
          Serassi M
          Scabini M
          Vercelli A
          Tinelli C
          Dal Bello B
          Burns PN
          Calliada F
          Rossi, Sandro
          Ghittoni, Giorgia
          Ravetta, Valentina
          Torello Viera, Francesca
          Rosa, Laura
          Serassi, Martina
          Scabini, Mara
          Vercelli, Alessandro
        affil: VI Department of Internal Medicine and Interventional Ultrasonography, Policlinico S. Matteo Foundation, IRCCS, P.le Golgi n. 19, 27100, Pavia, Italy
      sug:
        subj:
          Carcinoma, Hepatocellular Complications
          Carcinoma, Hepatocellular Diagnosis
          Liver Neoplasms Complications
          Liver Neoplasms Diagnosis
          Portal Vein Radiography
          Portal Vein Ultrasonography
          Venous Thrombosis Complications
          Venous Thrombosis Diagnosis
          Aged
          Contrast Media
          Female
          Male
          Reproducibility of Results
          Sensitivity and Specificity
          Tomography, X-Ray Computed Methods
          Ultrasonography Methods
          Human
          Aged: 65+ years
          Female
          Male
      ab: The aim was to compare the performances of contrast-enhanced (CE) ultrasonography (US) and spiral computed tomography (CT) in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma (HCC). We studied 50 patients with HCC who had biopsy-proven portal vein thrombi that had been detected with US and color Doppler US. Thirteen of the thrombi involved the main portal trunk and 37 the segmental branches. CEUS and CT were performed within a week of thrombus biopsies. For each imaging technique, diagnoses of thrombosis (present/absent) and thrombus nature (malignancy/benignancy) were made by experienced readers under blinded conditions and compared with pathological findings to determine accuracy rates for thrombus detection and characterization. Forty-four of the 50 thrombi were pathologically diagnosed as malignant and the remaining six were benign. CEUS detected 50/50 (100%) thrombi and correctly characterized 49/50 (98%). CT detected 34/50 (68%) thrombi and correctly characterized 23 of these 34 (68%). CEUS outperformed CT in terms of both thrombus detection (P < 0.0001) and characterization (P = 0.0001). CEUS appears to be significantly superior to CT for detection and characterization of portal vein thrombosis complicating HCC, and it should be considered in the staging of these tumors.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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