Receptor guided 3D-QSAR: a useful approach for designing of IGF-1R inhibitors.
Research by other investigators has established that insulin-like growth factor-1 receptor (IGF-1R) is a key oncological target, and that derivatives of 1, 3-disubstituted-imidazo[1,5-alpha] pyrazine are potent IGF-1R inhibitors. In this paper, we report on our three-dimensional quantitative structu...
| Publicado en: | Journal of Biomedicine & Biotechnology pp. 9p - 10 |
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| Autores principales: | , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
2008 Regular issue
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| Acceso en línea: | Ver este registro en EBSCOhost |