Effect of nebicapone on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Nebicapone is a new catechol-O-methyltransferase inhibitor. In vitro, nebicapone has showed an inhibitory effect upon CYP2C9, which is responsible for the metabolism of S-warfarin. The objective of this study was to investigate the effect of nebicapone on warfarin pharmacokinetics and pharmacodynami...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 64; no. 10; pp. 961 - 967 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Oct2008
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| Acceso en línea: | Ver este registro en EBSCOhost |