Diagnostic value of endomyocardial biopsy guided by electroanatomic voltage mapping in arrhythmogenic right ventricular cardiomyopathy/dysplasia.
Introduction: To improve the endomyocardial biopsy (EMB) diagnostic sensitivity for arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D), we hypothesized a biopsy sampling focused on selected right ventricle (RV) low-voltage areas identified by electroanatomic voltage mapping. Methods...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 19; no. 11; pp. 1127 - 1135 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Nov2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105569617&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105569617 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Nov2008 vid: 19 iid: 11 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 105569617 2010092835 10.1111/j.1540-8167.2008.01228.x NLM18554207 105569617 ppf: 1127 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Diagnostic value of endomyocardial biopsy guided by electroanatomic voltage mapping in arrhythmogenic right ventricular cardiomyopathy/dysplasia. aug: au: Avella A d'Amati G Pappalardo A Re F Silenzi PF Laurenzi F De Girolamo P Pelargonio G Dello Russo A Baratta P Messina G Zecchi P Zachara E Tondo C affil: Cardiology Division, Cardiac Arrhythmia and Heart Failure Research Institute, St. Camillo-Forlanini Hospital/Catholic University of Sacred Heart, Rome, Italy sug: subj: Body Surface Potential Mapping Myocardial Diseases Diagnosis Adult Biopsy Methods Comparative Studies Female Fisher's Exact Test Heart Ventricle Male Sensitivity and Specificity Two-Tailed Test Human Adult: 19-44 years Female Male ab: Introduction: To improve the endomyocardial biopsy (EMB) diagnostic sensitivity for arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D), we hypothesized a biopsy sampling focused on selected right ventricle (RV) low-voltage areas identified by electroanatomic voltage mapping. Methods and Results: The study population (22 patients, 10 men; mean age 34 ± 10 years) included 11 patients with overt ARVC/D (group A) and 11 patients with suspected ARVC/D (group B), according to both arrhythmic profile and standardized noninvasive diagnostic criteria. In all 22 patients, an RV bipolar voltage mapping was performed with CARTO[TM] system sampling multiple endocardial sites (262 ± 61), during sinus rhythm, with a 0.5-1.5 mV color range setting of voltage display. All 11 (100%) group A patients and 8 of the 11 (73%) group B patients (P = nonsignificant [NS]) presented RV low-voltage areas (<0.5 mV). In 8 group A patients and in all 8 group B patients with a pathological RV voltage map, an EMB focused on the low-voltage areas was performed. In 6 (75%) group A patients and in 7 (87%) group B patients (P = NS), voltage mapping-guided EMB was diagnostic for ARVC/D. In the remaining 3 patients, only nonspecific histological findings were observed. Conclusions: The results of our study (1) confirm the high diagnostic sensitivity of RV voltage mapping in patients with overt ARVC/D, (2) document a high prevalence of RV low-voltage areas even in patients with suspected ARVC/D, and (3) demonstrate that in patients with clinical evidence or suspicion for ARVC/D, presenting RV low-voltage areas, EMB guided by voltage mapping may provide ARVC/D diagnosis confirmation. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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