Peripheral contrast-enhanced MR angiography at 3.0T, improved spatial resolution and low dose contrast: initial clinical experience.

To investigate a high spatial resolution peripheral contrast-enhanced MR angiography (CE-MRA) protocol, applying a dedicated multi-channel array coil and accelerated parallel acquisition at 3.0T in evaluation of patients with peripheral vascular disease. Twenty patients with peripheral vascular dise...

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Publicado en:European Radiology Vol. 18; no. 12; pp. 2893 - 2901
Autores principales: Nael K, Krishnam M, Nael A, Ton A, Ruehm SG, Finn JP, Nael, Kambiz, Krishnam, Mayil, Nael, Ali, Ton, Anthony, Ruehm, Stefan G, Finn, J Paul
Formato: research Journal Article
Publicado: Springer Nature Dec2008
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2008
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      pub: Springer Nature
      place: New York, New York
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        atl: Peripheral contrast-enhanced MR angiography at 3.0T, improved spatial resolution and low dose contrast: initial clinical experience.
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          Nael K
          Krishnam M
          Nael A
          Ton A
          Ruehm SG
          Finn JP
          Nael, Kambiz
          Krishnam, Mayil
          Nael, Ali
          Ton, Anthony
          Ruehm, Stefan G
          Finn, J Paul
        affil: Department of Radiological Sciences, David Geffen School of Medicine at University of California Los Angeles, 10945 Le Conte Avenue, Suite # 3371, Los Angeles, CA 90095-7206, USA
      sug:
        subj:
          Contrast Media Administration and Dosage
          Contrast Media Diagnostic Use
          Image Enhancement Methods
          Magnetic Resonance Angiography Methods
          Peripheral Vascular Diseases Diagnosis
          Aged
          Aged, 80 and Over
          Dose-Response Relationship, Drug
          Female
          Male
          Middle Age
          Observer Bias
          Reproducibility of Results
          Sensitivity and Specificity
          Human
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: To investigate a high spatial resolution peripheral contrast-enhanced MR angiography (CE-MRA) protocol, applying a dedicated multi-channel array coil and accelerated parallel acquisition at 3.0T in evaluation of patients with peripheral vascular disease. Twenty patients with peripheral vascular disease underwent multi-station high spatial resolution peripheral CE-MRA at 3T. The image quality, presence of venous contamination, image noise, and artifact were evaluated by 2 radiologists independently. Assessment of arterial disease for 540 arterial segments was performed, and findings were correlated with conventional catheter angiography in 10 patients. All studies were yielded high diagnostic image quality. Venous contamination and artifact were minimal and never interfered with diagnosis. Sixty seven arterial segments with significant stenoses (>0%) were detected by observers with excellent interobserver agreement (kappa = 0.82; 95% CI: 0.76, 0.88). There was a significant correlation between CE-MRA and conventional angiography (Rs = 0.91 and 0.94 for reader 1 and 2, respectively) for the assessment of the degree of stenosis. Higher available SNR at 3T in combination with multi-coil technology and accelerated parallel acquisition, result in acquisition of nearly isotropic submillimeter 3D voxels throughout the entire peripheral arterial tree with diagnostic image quality and favorable comparative analysis with catheter angiography.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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