MRI-based anatomical model of the human head for specific absorption rate mapping.

In this study, we present a magnetic resonance imaging (MRI)-based, high-resolution, numerical model of the head of a healthy human subject. In order to formulate the model, we performed quantitative volumetric segmentation on the human head, using T1-weighted MRI. The high spatial resolution used (...

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Publicado en:Medical & Biological Engineering & Computing Vol. 46; no. 12; pp. 1239 - 1252
Autores principales: Makris N, Angelone L, Tulloch S, Sorg S, Kaiser J, Kennedy D, Bonmassar G, Makris, Nikos, Angelone, Leonardo, Tulloch, Seann, Sorg, Scott, Kaiser, Jonathan, Kennedy, David, Bonmassar, Giorgio
Formato: research Journal Article
Publicado: Springer Nature Dec2008
Acceso en línea:Ver este registro en EBSCOhost
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        atl: MRI-based anatomical model of the human head for specific absorption rate mapping.
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          Makris N
          Angelone L
          Tulloch S
          Sorg S
          Kaiser J
          Kennedy D
          Bonmassar G
          Makris, Nikos
          Angelone, Leonardo
          Tulloch, Seann
          Sorg, Scott
          Kaiser, Jonathan
          Kennedy, David
          Bonmassar, Giorgio
        affil: Department of Psychiatry, Neurology and Radiology Services, Center for Morphometric Analysis, HST Athinoula A. Martinos Center, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02129, USA
      sug:
        subj:
          Cephalometry Methods
          Head Anatomy and Histology
          Models, Anatomic
          Adult
          Brain Mapping Methods
          Brain Anatomy and Histology
          Electromagnetic Fields
          Image Processing, Computer Assisted Methods
          Magnetic Resonance Imaging Methods
          Male
          Human
          Adult: 19-44 years
          Male
      ab: In this study, we present a magnetic resonance imaging (MRI)-based, high-resolution, numerical model of the head of a healthy human subject. In order to formulate the model, we performed quantitative volumetric segmentation on the human head, using T1-weighted MRI. The high spatial resolution used (1 x 1 x 1 mm(3)), allowed for the precise computation and visualization of a higher number of anatomical structures than provided by previous models. Furthermore, the high spatial resolution allowed us to study individual thin anatomical structures of clinical relevance not visible by the standard model currently adopted in computational bioelectromagnetics. When we computed the electromagnetic field and specific absorption rate (SAR) at 7 Tesla MRI using this high-resolution model, we were able to obtain a detailed visualization of such fine anatomical structures as the epidermis/dermis, bone structures, bone-marrow, white matter and nasal and eye structures.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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