Development of a rapid screening instrument for mild cognitive impairment and undiagnosed dementia.

Mild cognitive impairment (MCI) often presages development of Alzheimer's disease (AD). We recently completed a cross-sectional study to test the hypothesis that a combination of a brief cognitive screening instrument (Mini-Cog) with a functional scale (Functional Activities Questionnaire; FAQ) woul...

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Publicado en:Journal of Alzheimer's Disease Vol. 15; no. 3; pp. 419 - 428
Autores principales: Steenland NK, Auman CM, Patel PM, Bartell SM, Goldstein FC, Levey AI, Lah JJ, Steenland, N Kyle, Auman, Courtney M, Patel, Purvi M, Bartell, Scott M, Goldstein, Felicia C, Levey, Allan I, Lah, James J
Formato: research Journal Article
Publicado: Sage Publications Inc. 2008
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Sage Publications Inc.
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        atl: Development of a rapid screening instrument for mild cognitive impairment and undiagnosed dementia.
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        au:
          Steenland NK
          Auman CM
          Patel PM
          Bartell SM
          Goldstein FC
          Levey AI
          Lah JJ
          Steenland, N Kyle
          Auman, Courtney M
          Patel, Purvi M
          Bartell, Scott M
          Goldstein, Felicia C
          Levey, Allan I
          Lah, James J
        affil: Department of Environmental and Occupational Health, School of Public Health, Emory University, Atlanta, GA 30322, USA
      sug:
        subj:
          Cognition Disorders Diagnosis
          Cognition Disorders Psychosocial Factors
          Dementia Diagnosis
          Dementia Psychosocial Factors
          Activities of Daily Living
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          Attention
          Female
          Language
          Logistic Regression
          Male
          Memory
          Predictive Value of Tests
          Psychomotor Performance
          Questionnaires
          Regression
          Spatial Perception
          Visual Perception Physiology
          Human
          Aged: 65+ years
          Female
          Male
      ab: Mild cognitive impairment (MCI) often presages development of Alzheimer's disease (AD). We recently completed a cross-sectional study to test the hypothesis that a combination of a brief cognitive screening instrument (Mini-Cog) with a functional scale (Functional Activities Questionnaire; FAQ) would accurately identify individuals with MCI and undiagnosed dementia. The Mini-Cog consists of a clock drawing task and 3-item recall, and takes less than 5 minutes to administer. The FAQ is a 30-item questionnaire completed by an informant. In addition to the Mini-Cog and FAQ, a traditional cognitive test battery was administered, and two neurologists and a neuropsychologist determined a consensus diagnosis of Normal, MCI, or Dementia. A classification tree algorithm was used to pick optimal cutpoints, and, using these cutpoints, the combined Mini-Cog and FAQ (MC-FAQ) predicted the consensus diagnosis with an accuracy of 83% and a weighted kappa of 0.81. When the population was divided into Normal and Abnormal, the sensitivity, specificity and positive predictive value were 89%, 90%, and 95%, respectively. The MC-FAQ discriminates individuals with MCI from cognitively normal individuals and those with dementia, and its ease of administration makes it an attractive screening instrument to aid detection of cognitive impairment in the elderly.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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