Delayed diagnosis of pyoderma gangrenosum: a case study.

Pyoderma gangrenosum (PD) is a rare, chronic, relapsing, ulcerative, neutrophilic cutaneous disease and may be difficult to recognize. It is not uncommon for PD to be mistakenly diagnosed as vascular occlusive or venous disease, vasculitis, cancer, infection, exogenous tissue injury, or other inflam...

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Publicado en:Ostomy Wound Management Vol. 54; no. 11; pp. 32 - 37
Autores principales: Contreras-Ruiz J, Kresch-Tronik NS, de la Cruz-Garcia MI, Mercado-Ceja S, Lozano-Platonoff A
Formato: case study pictorial review Journal Article
Publicado: HMP Global 2008 Nov
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2008 Nov
      vid: 54
      iid: 11
      pid: 20465
      pub: HMP Global
      place: Malvern, Pennsylvania
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        atl: Delayed diagnosis of pyoderma gangrenosum: a case study.
      aug:
        au:
          Contreras-Ruiz J
          Kresch-Tronik NS
          de la Cruz-Garcia MI
          Mercado-Ceja S
          Lozano-Platonoff A
        affil: Interdisciplinary Wound and Ostomy Care Center (IWOCC), Tlalpan, D.F., Mexico; Email: contruiz@gmail.com
      sug:
        subj:
          Diagnosis, Delayed
          Pyoderma Gangrenosum Diagnosis
          Administration, Topical
          Biopsy
          Female
          Immunosuppressive Agents Administration and Dosage
          Mexico
          Middle Age
          Prednisone Therapeutic Use
          Pyoderma Gangrenosum Drug Therapy
          Pyoderma Gangrenosum Pathology
          Pyoderma Gangrenosum Symptoms
          Pyoderma Gangrenosum Therapy
          Wound Healing
          Middle Aged: 45-64 years
          Female
      ab: Pyoderma gangrenosum (PD) is a rare, chronic, relapsing, ulcerative, neutrophilic cutaneous disease and may be difficult to recognize. It is not uncommon for PD to be mistakenly diagnosed as vascular occlusive or venous disease, vasculitis, cancer, infection, exogenous tissue injury, or other inflammatory disorders. A 55-year-old woman with a 5-year history of a very painful and enlarging ulcer presented at the authors' clinic. Previously, based on an original diagnosis of venous ulcer, the wound had been surgically debrided and managed with saline-soaked gauze and compression therapy. After the authors secured a complete history (which included rheumatoid arthritis) and assessment, PD was suspected. A biopsy was performed for histological confirmation. Pyoderma gangrenosum treatment, including oral corticosteroids and topical 0.01% tacrolimus twice daily covered with nonadhesive gauze and compression wrapping, was started. After 4 weeks, the wound had improved noticeably and pain medications to manage wound pain were discontinued. The wound was completely healed after 4 months. The presence or absence of PD must be ascertained in all patients who present with a history of painful lower leg ulcers and PD risk factors, such as rheumatoid arthritis.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        review
        Journal Article
      ougenre: Article
    language: English
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