Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates.

BACKGROUND: Widespread residential pesticide use throughout the United States has resulted in ubiquitous, low-level pesticide exposure. The mix of active pesticide ingredients is changing in response to 2000--2001 regulations restricting use of the organophosphorus insecticides chlorpyrifos and diaz...

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Publicado en:Environmental Health Perspectives Vol. 116; no. 12; pp. 1681 - 1689
Autores principales: Williams MK, Rundle A, Holmes D, Reyes M, Hoepner LA, Barr DB, Camann DE, Perera FP, Whyatt RM
Formato: research tables/charts Journal Article
Publicado: National Institute of Environmental Health Sciences Dec2008
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2008
      vid: 116
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      pub: National Institute of Environmental Health Sciences
      place: Research Triangle Park, North Carolina
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        atl: Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates.
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        au:
          Williams MK
          Rundle A
          Holmes D
          Reyes M
          Hoepner LA
          Barr DB
          Camann DE
          Perera FP
          Whyatt RM
        affil: Columbia Center for Children's Environmental Health, Mailman School of Public Health, Columbia University, New York, New York, USA
      sug:
        subj:
          Air Pollution, Indoor
          Environmental Exposure In Pregnancy
          Insecticides Adverse Effects
          Pest Control
          Analysis of Variance
          Chi Square Test
          Comparative Studies
          Environmental Monitoring
          Female
          Funding Source
          Kruskal-Wallis Test
          Linear Regression
          Logistic Regression
          Mann-Whitney U Test
          Multivariate Statistics
          New York
          Nonparametric Statistics
          Parametric Statistics
          Pregnancy
          Prospective Studies
          Questionnaires
          Spearman's Rank Correlation Coefficient
          T-Tests
          United States
          United States Environmental Protection Agency
          Univariate Statistics
          Human
          Female
      ab: BACKGROUND: Widespread residential pesticide use throughout the United States has resulted in ubiquitous, low-level pesticide exposure. The mix of active pesticide ingredients is changing in response to 2000--2001 regulations restricting use of the organophosphorus insecticides chlorpyrifos and diazinon. OBJECTIVES: We aimed to determine the impact of U.S. Environmental Protection Agency regulations on pest infestation levels, pesticide use, and pesticides measured in indoor air samples. METHODOLOGY: 511 pregnant women from inner-city New York were enrolled between 2000 and 2006. Permethrin, a pyrethroid insecticide; piperonyl butoxide (PBO), a pyrethroid synergist; chlorpyrifos; and diazinon were measured in 48-hr prenatal personal air samples. Data on pest infestation and pesticide use were collected via questionnaire. RESULTS: Eighty-eight percent of women reported using pesticides during pregnancy; 55% reported using higher-exposure pesticide applications (spray cans, pest bombs and/or professional pesticide applicators). Self-reported pest sightings and use of higher-exposure applications increased significantly after the regulations were implemented (p < 0.001). PBO, cis-, and trans-permethrin were detected in 75, 19, and 18% of personal air samples, respectively. Detection frequencies of PBO and cis- and trans-permethrin increased significantly over time (p < 0.05 controlling for potential confounders). Levels and/or detection frequencies of these compounds were significantly higher among mothers reporting use of high exposure pesticide applications (p <= 0.05). Chlorpyrifos and diazinon levels decreased significantly over time (p < 0.001). CONCLUSION: In this cohort, pest infestations, use of pesticides, and use of permethrin appear to increase after the residential restriction of organophosphorus insecticides. This is one of the first studies to document widespread residential exposure to PBO.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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