MR elastography of liver fibrosis: preliminary results comparing spin-echo and echo-planar imaging.

The purpose of this study was to prospectively compare the performance of magnetic resonance (MR) elastography using echo-planar and spin-echo imaging for staging of hepatic fibrosis. Twenty-four patients who had liver biopsy for suspicion of chronic liver disease had MR elastography performed with...

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Publicado en:European Radiology Vol. 18; no. 11; pp. 2535 - 2542
Autores principales: Huwart L, Salameh N, Ter Beek L, Vicaut E, Peeters F, Sinkus R, Van Beers BE, Huwart, Laurent, Salameh, Najat, ter Beek, Leon, Vicaut, Eric, Peeters, Frank, Sinkus, Ralph, Van Beers, Bernard E
Formato: research Journal Article
Publicado: Springer Nature Nov2008
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2008
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-008-1051-5
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        atl: MR elastography of liver fibrosis: preliminary results comparing spin-echo and echo-planar imaging.
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          Huwart L
          Salameh N
          Ter Beek L
          Vicaut E
          Peeters F
          Sinkus R
          Van Beers BE
          Huwart, Laurent
          Salameh, Najat
          ter Beek, Leon
          Vicaut, Eric
          Peeters, Frank
          Sinkus, Ralph
          Van Beers, Bernard E
        affil: Diagnostic Radiology Unit, Université Catholique de Louvain, St-Luc University Hospital, Brussels, Belgium
      sug:
        subj:
          Liver Cirrhosis Diagnosis
          Magnetic Resonance Imaging Methods
          Ultrasonography Methods
          Adult
          Aged
          Female
          Male
          Middle Age
          Oxides
          Pilot Studies
          Reproducibility of Results
          Sensitivity and Specificity
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: The purpose of this study was to prospectively compare the performance of magnetic resonance (MR) elastography using echo-planar and spin-echo imaging for staging of hepatic fibrosis. Twenty-four patients who had liver biopsy for suspicion of chronic liver disease had MR elastography performed with both spin-echo and echo-planar sequences. At histology, the fibrosis stage was assessed according to METAVIR. The data acquisition time was about 20 min using spin-echo, and only 2 min using echo-planar imaging. The hepatic signal-to-noise ratios were similar on both images (22.51 +/- 5.37 for spin-echo versus 21.02 +/- 4.76 for echo-planar, p = 0.33). The elasticity measurements and the fibrosis stages were strongly correlated. The Spearman correlation coefficients were r = 0.91 (p < 0.01) with spin-echo and r = 0.84 (p < 0.01) with echo-planar sequences. These correlation coefficients did not differ significantly (p = 0.17). A strong correlation was also observed between spin-echo and echo-planar elasticity (r = 0.83, p < 0.001), without systematic bias. The results of our study showed that echo-planar imaging substantially decreased the data acquisition time of MR elastography, while maintaining the image quality and diagnostic performance for staging of liver fibrosis. This suggests that echo-planar MR elastography could replace spin-echo MR elastography in clinical practice.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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