Dual-energy CT of the heart for diagnosing coronary artery stenosis and myocardial ischemia-initial experience.
We aimed to evaluate the feasibility of diagnosing coronary stenosis and myocardial ischemia with a single dual-energy CT (DECT) acquisition. Thirty-five patients underwent contrast-enhanced, ECG-gated DECT of the heart while independently operating the two tubes of a dual-source CT system at high-...
| Publicado en: | European Radiology Vol. 18; no. 11; pp. 2414 - 2425 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Nov2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105617869&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105617869 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Nov2008 vid: 18 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105617869 34723017 NLM18523782 2010158811 10.1007/s00330-008-1022-x NLM18523782 105617869 ppf: 2414 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Dual-energy CT of the heart for diagnosing coronary artery stenosis and myocardial ischemia-initial experience. aug: au: Ruzsics B Lee H Zwerner PL Gebregziabher M Costello P Schoepf UJ Ruzsics, Balazs Lee, Heon Zwerner, Peter L Gebregziabher, Mulugeta Costello, Philip Schoepf, U Joseph affil: Department of Radiology, Medical University of South Carolina, Charleston, SC 29425, USA sug: subj: Algorithms Coronary Angiography Methods Coronary Stenosis Complications Coronary Stenosis Radiography Myocardial Ischemia Etiology Myocardial Ischemia Radiography Tomography, X-Ray Computed Methods Female Male Middle Age Pilot Studies Radiographic Image Enhancement Methods Radiographic Image Interpretation, Computer-Assisted Methods Reproducibility of Results Sensitivity and Specificity Human Middle Aged: 45-64 years Female Male ab: We aimed to evaluate the feasibility of diagnosing coronary stenosis and myocardial ischemia with a single dual-energy CT (DECT) acquisition. Thirty-five patients underwent contrast-enhanced, ECG-gated DECT of the heart while independently operating the two tubes of a dual-source CT system at high- and low-energy X-ray spectra. From the same raw data, coronary CTA (cCTA) studies were reconstructed for stenosis detection, and the myocardial blood-pool was analyzed by determining the tissue iodine content. Two independent observers analyzed all studies for stenosis and myocardial blood-pool deficits. Results were correlated with SPECT, coronary catheterization and cCTA on a segmental basis. cCTA had 98% sensitivity, 88% specificity and 92% accuracy for detection of >50% stenosis. DECT detected myocardial ischemia with 84% sensitivity, 94% specificity and 92% accuracy. Our initial experience may warrant further exploration of DECT as a possibly feasible single imaging investigation for the comprehensive diagnosis of coronary stenosis and myocardial ischemia. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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