Transitions in and out of alcohol use disorders: their associations with conditional changes in quality of life over a 3-year follow-up interval.

Abstract Aims: The aim of this study was to investigate longitudinal changes in quality of life (QOL) as a function of transitions in alcohol use disorders (AUD) over a 3-year follow-up of a general US population sample. Methods: The analysis is based on individuals who drank alcohol in the year pre...

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Publicado en:Alcohol & Alcoholism Vol. 44; no. 1; pp. 84 - 93
Autores principales: Dawson DA, Li TK, Chou SP, Grant BF
Formato: research Journal Article
Publicado: Oxford University Press / USA Jan/Feb2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan/Feb2009
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        atl: Transitions in and out of alcohol use disorders: their associations with conditional changes in quality of life over a 3-year follow-up interval.
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          Dawson DA
          Li TK
          Chou SP
          Grant BF
        affil: Laboratory of Biometry and Epidemiology, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892-9304, USA. ddawson@mail.nih.gov
      sug:
        subj:
          Alcoholism Psychosocial Factors
          Quality of Life
          Adolescence
          Adult
          Alcoholism Epidemiology
          Female
          Health Status
          Human Activities
          Linear Regression
          Male
          Models, Statistical
          Pain Complications
          Pain Psychosocial Factors
          Prospective Studies
          Psychological Tests
          Reproducibility of Results
          Surveys
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Female
          Male
      ab: Abstract Aims: The aim of this study was to investigate longitudinal changes in quality of life (QOL) as a function of transitions in alcohol use disorders (AUD) over a 3-year follow-up of a general US population sample. Methods: The analysis is based on individuals who drank alcohol in the year preceding the Wave 1 National Epidemiologic Survey on Alcohol and Related Conditions and were reinterviewed at Wave 2 (n = 22,245). Using multiple linear regression models, changes in SF-12 QOL were estimated as a function of DSM-IV AUD transitions, controlling for baseline QOL and multiple potential confounders. Results: Onset and offset of AUD were strongly associated with changes in mental/psychological functioning, with significant decreases in mental component summary (NBMCS) scores among individuals who developed dependence and significant increases among those who achieved full and partial remission from dependence. The increases in overall NBMCS and its social functioning, role emotional and mental health components were equally great for abstinent and nonabstinent remission from dependence, but improvements in bodily pain and general health were associated with nonabstinent remission only. Onset of abuse was unrelated to changes in QOL, and the increase in NBMCS associated with nonabstinent remission from abuse only was slight. Individuals with abuse only or no AUD who stopped drinking had significant declines in QOL. Conclusions: These results suggest the possible importance of preventing and treating AUD for maintaining and/or improving QOL. They are also consistent with the sick quitter hypothesis and suggest that abuse is less a mental disorder than a maladaptive pattern of behavior.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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