Evaluation of right ventricular function with multidetector computed tomography: comparison with magnetic resonance imaging and analysis of inter- and intraobserver variability.

This study was performed to prospectively compare multidetector computed tomography (MDCT) with 16 simultaneous sections and magnetic resonance imaging (MRI) for the assessment of global right ventricular function in 50 patients. MDCT using a semiautomatic analysis tool showed good correlation with...

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Published in:European Radiology Vol. 19; no. 2; pp. 278 - 290
Main Authors: Müller M, Teige F, Schnapauff D, Hamm B, Dewey M, Müller, Mira, Teige, Florian, Schnapauff, Dirk, Hamm, Bernd, Dewey, Marc
Format: research Journal Article
Published: Springer Nature Feb2009
Online Access:View this record in EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Evaluation of right ventricular function with multidetector computed tomography: comparison with magnetic resonance imaging and analysis of inter- and intraobserver variability.
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          Müller M
          Teige F
          Schnapauff D
          Hamm B
          Dewey M
          Müller, Mira
          Teige, Florian
          Schnapauff, Dirk
          Hamm, Bernd
          Dewey, Marc
        affil: Department of Radiology, Charité, Medical School, Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, PO Box 10098, Germany
      sug:
        subj:
          Cardiovascular System Physiology
          Magnetic Resonance Imaging Methods
          Tomography, X-Ray Computed Methods
          Adult
          Aged
          Cardiology Methods
          Female
          Male
          Middle Age
          Observer Bias
          Prospective Studies
          Reproducibility of Results
          Software
          Systole
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: This study was performed to prospectively compare multidetector computed tomography (MDCT) with 16 simultaneous sections and magnetic resonance imaging (MRI) for the assessment of global right ventricular function in 50 patients. MDCT using a semiautomatic analysis tool showed good correlation with MRI for end-diastolic volume (EDV, r=0.83, p<0.001), end-systolic volume (ESV, r=0.86, p<0.001) and stroke volume (SV, r=0.74, p<0.001), but only a moderate correlation for the ejection fraction (EF, r=0.67, p<0.001). Bland Altman analysis revealed a slight, but insignificant overestimation of EDV (4.0 ml, p=0.08) and ESV (2.4 ml, p=0.07), and underestimation of EF (0.1%, p=0.92) with MDCT compared with MRI. All limits of agreement between both modalities (EF: +/-15.7%, EDV: +/-31.0 ml, ESV: +/-18.0 ml) were in a moderate but acceptable range. Interobserver variability of MDCT was not significantly different from that of MRI. For MDCT software, the post-processing time was significantly longer (19.6+/-5.8 min) than for MRI (11.8+/-2.6 min, p<0.001). Accurate assessment of right ventricular volumes by 16-detector CT is feasible but still rather time-consuming.
      pubtype: Academic Journal
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        research
        Journal Article
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    language: English
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