Total-body contrast-enhanced MRA on a short, wide-bore 1.5-T system: intra-individual comparison of Gd-BOPTA and Gd-DOTA.
Total-body contrast-enhanced MRA (CE-MRA) provides information of the entire vascular system according to a one-stop-shop approach. Short, wide-bore scanners have not yet been used for total-body CE-MRA, probably due to their restricted field of view in the z-direction. The purpose of this feasibili...
| Publicado en: | European Radiology Vol. 18; no. 10; pp. 2265 - 2274 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | clinical trial research Journal Article |
| Publicado: |
Springer Nature
Oct2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105626694&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105626694 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Oct2008 vid: 18 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105626694 34227637 NLM18431575 2010157784 10.1007/s00330-008-0976-z NLM18431575 105626694 ppf: 2265 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Total-body contrast-enhanced MRA on a short, wide-bore 1.5-T system: intra-individual comparison of Gd-BOPTA and Gd-DOTA. aug: au: Rasmus M Bremerich J Egelhof T Huegli RW Bongartz G Bilecen D Rasmus, M Bremerich, J Egelhof, T Huegli, R W Bongartz, G Bilecen, D affil: Department of Radiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland sug: subj: Arteries Anatomy and Histology Diagnostic Imaging Methods Heterocyclic Compounds Diagnostic Use Magnetic Resonance Angiography Equipment and Supplies Magnetic Resonance Angiography Methods Organic Chemicals Diagnostic Use Sorbitol Adult Clinical Trials Contrast Media Equipment Design Equipment Failure Female Male Middle Age Pilot Studies Sorbitol Diagnostic Use Human Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Total-body contrast-enhanced MRA (CE-MRA) provides information of the entire vascular system according to a one-stop-shop approach. Short, wide-bore scanners have not yet been used for total-body CE-MRA, probably due to their restricted field of view in the z-direction. The purpose of this feasibility study is to introduce an image protocol for total-body MRA on a short, wide-bore system. The protocol includes five to six table-moving steps and two injection runs. Two pharmacologically different contrast materials (CM) were applied in ten healthy volunteers in view of possible CM-dependent influences on the protocol outcome (Gd-Bopta, Gd-Dota). Differences consisted of significantly higher CNR with Gd-Bopta with a mean of 73.8+/-38.7 versus 69.1+/-34.3 (p=0.008), significantly better arterial visualization values with Gd-Dota with a mean of 1.26+/-0.44 versus 1.53+/-0.73 (p=0.003) and a tendency to less venous overlay with Gd-Dota, mean 1.19+/-0.44 and 1.34+/-0.72, respectively (p=0.065) (two-tailed Wilcoxon matched-pairs test). Overall 94% of the steps were valued as qualitatively excellent or good. The good results with both CM suggest a transfer to further patient evaluation. pubtype: Academic Journal doctype: clinical trial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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