Segmental enhancement on breast MR images: differential diagnosis and diagnostic strategy.

The histopathological variations of segmental enhancement on breast magnetic resonance imaging (MRI) were investigated, with the aim of identifying imaging characteristic clues to their differential diagnosis. We reviewed 70 breast MRI examinations demonstrating segmental enhancement, classified the...

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Publicado en:European Radiology Vol. 18; no. 10; pp. 2067 - 2076
Autores principales: Yuen S, Uematsu T, Masako K, Uchida Y, Nishimura T, Yuen, Sachiko, Uematsu, Takayoshi, Masako, Kasami, Uchida, Yoshihiro, Nishimura, Tsunehiko
Formato: research Journal Article
Publicado: Springer Nature Oct2008
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Segmental enhancement on breast MR images: differential diagnosis and diagnostic strategy.
      aug:
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          Yuen S
          Uematsu T
          Masako K
          Uchida Y
          Nishimura T
          Yuen, Sachiko
          Uematsu, Takayoshi
          Masako, Kasami
          Uchida, Yoshihiro
          Nishimura, Tsunehiko
        affil: Division of Diagnostic Radiology, Shizuoka Cancer Center Hospital, Shizuoka, 411-8777, Japan
      sug:
        subj:
          Algorithms
          Breast Neoplasms Diagnosis
          Breast Pathology
          Image Enhancement Methods
          Image Interpretation, Computer Assisted Methods
          Information Science Methods
          Magnetic Resonance Imaging Methods
          Adult
          Diagnosis, Differential
          Female
          Middle Age
          Reproducibility of Results
          Sensitivity and Specificity
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
      ab: The histopathological variations of segmental enhancement on breast magnetic resonance imaging (MRI) were investigated, with the aim of identifying imaging characteristic clues to their differential diagnosis. We reviewed 70 breast MRI examinations demonstrating segmental enhancement, classified them based on their histopathology, and assessed their MRI findings as follows: (1) confluent or not confluent, (2) late enhancement pattern, and the absence or presence of (3) clustered ring enhancements and (4) surrounding high signal intensity (SI) on T2-weighted imaging. Thirteen lesions (18.5%) were benign, eight (11.5%) were high risk, 25 (36%) were ductal carcinoma in situ (DCIS) and 24 (34%) were infiltrating mammary carcinomas (IMC). Clustered ring enhancements were demonstrated in 74% of malignancies (high risk, DCIS and IMC) but no benign lesions (P=0.0001). The surrounding high SI on T2-weighted imaging was seen in four of five IMC with marked lymphatic involvement. Clustered ring enhancement was not demonstrated in six of seven IMC of tubular and/or lobular types. Segmental enhancement was seen in not only DCIS but also IMC, high-risk and benign lesions. Clustered ring enhancement and surrounding high SI on T2-weighted imaging were clues to their differential diagnosis and helpful to decide their diagnostic strategy.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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