Planning study comparison of real-time target tracking and four-dimensional inverse planning for managing patient respiratory motion.
Purpose: Real-time target tracking (RT-TT) and four-dimensional inverse planning (4D-IP) are two potential methods to manage respiratory target motion. In this study, we evaluated each method using the cumulative dose-volume criteria in lung cancer radiotherapy. Methods and Materials: Respiration-co...
| Publicado en: | International Journal of Radiation Oncology, Biology, Physics Vol. 72; no. 4; pp. 1221 - 1228 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Pergamon Press - An Imprint of Elsevier Science
Nov2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105627803&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105627803 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03603016 1ZQ jtl: International Journal of Radiation Oncology, Biology, Physics issn: 03603016 maglogo: N pubinfo: dt: Nov2008 vid: 72 iid: 4 pid: 2410 pub: Pergamon Press - An Imprint of Elsevier Science artinfo: ui: 105627803 105627803 NLM18954716 2010159923 10.1016/j.ijrobp.2008.07.025 NLM18954716 105627803 ppf: 1221 ppct: 7 formats: tig: atl: Planning study comparison of real-time target tracking and four-dimensional inverse planning for managing patient respiratory motion. aug: au: Zhang P Hugo GD Yan D Zhang, Peng Hugo, Geoffrey D Yan, Di affil: Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073, USA sug: subj: Diagnostic Imaging Methods Neoplasms Radiography Neoplasms Radiotherapy Radiotherapy, Computer-Assisted Methods Respiratory Mechanics Tomography, X-Ray Computed Methods Artifacts Computer Systems Motion Reproducibility of Results Sensitivity and Specificity Human ab: Purpose: Real-time target tracking (RT-TT) and four-dimensional inverse planning (4D-IP) are two potential methods to manage respiratory target motion. In this study, we evaluated each method using the cumulative dose-volume criteria in lung cancer radiotherapy. Methods and Materials: Respiration-correlated computed tomography scans were acquired for 4 patients. Deformable image registration was applied to generate a displacement mapping for each phase image of the respiration-correlated computed tomography images. First, the dose distribution for the organs of interest obtained from an idealized RT-TT technique was evaluated, assuming perfect knowledge of organ motion and beam tracking. Inverse planning was performed on each phase image separately. The treatment dose to the organs of interest was then accumulated from the optimized plans. Second, 4D-IP was performed using the probability density function of respiratory motion. The beam arrangement, prescription dose, and objectives were consistent in both planning methods. The dose-volume and equivalent uniform dose in the target volume, lung, heart, and spinal cord were used for the evaluation. Results: The cumulative dose in the target was similar for both techniques. The equivalent uniform dose of the lung, heart, and spinal cord was 4.6 +/- 2.2, 11 +/- 4.4, and 11 +/- 6.6 Gy for RT-TT with a 0-mm target margin, 5.2 +/- 3.1, 12 +/- 5.9, and 12 +/- 7.8 Gy for RT-TT with a 2-mm target margin, and 5.3 +/- 2.3, 11.9 +/- 5.0, and 12 +/- 5.6 Gy for 4D-IP, respectively. Conclusion: The results of our study have shown that 4D-IP can achieve plans similar to those achieved by RT-TT. Considering clinical implementation, 4D-IP could be a more reliable and practical method to manage patient respiration-induced motion. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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