High prevalence of emphysema and its association with BMI: a study of smokers with normal spirometry.
OBJECTIVES: To evaluate to what extent emphysema was evident, as identified by High Resolution Computed Tomography (HRCT), in smokers with normal lung function and to relate age, gender, smoking history, and body mass index (BMI) to the HRCT results. A secondary aim was to study to what extent emphy...
| Publicado en: | Scandinavian Journal of Primary Health Care Vol. 26; no. 4; pp. 241 - 248 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Dec2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105637913&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105637913 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02813432 BDB jtl: Scandinavian Journal of Primary Health Care issn: 02813432 maglogo: Y pubinfo: dt: Dec2008 vid: 26 iid: 4 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 105637913 2010178615 10.1080/02813430802452732 NLM18846446 105637913 ppf: 241 ppct: 7 formats: fmt: @attributes: type: P tig: atl: High prevalence of emphysema and its association with BMI: a study of smokers with normal spirometry. aug: au: Stratelis G Fransson S Schmekel B Jakobsson P Mölstad S affil: Primary Care Centre, Vårdcentralen Brinken, Motala, Sweden. Georgios.Stratelis@blixtmail.se sug: subj: Body Mass Index Emphysema Epidemiology Smoking Spirometry Chi Square Test Data Analysis Software Data Analysis, Statistical Descriptive Statistics Female Fisher's Exact Test Forced Expiratory Volume Funding Source Male Middle Age P-Value Predictive Value of Tests Respiratory Function Tests T-Tests Tomography, X-Ray Computed Human Middle Aged: 45-64 years Female Male ab: OBJECTIVES: To evaluate to what extent emphysema was evident, as identified by High Resolution Computed Tomography (HRCT), in smokers with normal lung function and to relate age, gender, smoking history, and body mass index (BMI) to the HRCT results. A secondary aim was to study to what extent emphysema was present in smokers with lower normal values of lung function defined as FEV(1)/FVC ratio percentage of predicted value (89-93% of predicted value for males and 90-93% for females) or FEF(50) < or = 60% of predicted compared with smokers without this definition. METHODS: Fifty-nine smokers, with a mean age of 53 years and with normal lung function, were examined with HRCT. RESULTS: Emphysema evidenced visually by HRCT was present in 43% of the subjects. Using a 0-5 grade scale (0=normal finding; 5=emphysema in most slices), the degree of emphysema was almost exclusively 3-4. The type of emphysema was distributed as centrilobular emphysema predominant in 43.5%, paraseptal emphysema predominant in 43.5%, and as an equal mixture of these types in 13%. The presence of emphysema did not differ between the group of smokers with lower normal values of lung function and the rest of the smokers. Smokers with emphysema had significantly lower BMI than those devoid of emphysema, 24 and 27 respectively (p<0.0011). CONCLUSION: There was a high occurrence of visual emphysema in middle-aged smokers with normal lung function. The densitometric quantitative analysis method is inadequate for detecting mild emphysema. High prevalence of emphysema was associated with low BMI. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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