The feasibility of using Pareto fronts for comparison of treatment planning systems and delivery techniques.
Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitut...
| Publicado en: | Acta Oncologica Vol. 48; no. 2; pp. 233 - 238 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Medical Journals Sweden AB
Mar2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105644683&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105644683 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0284186X B84 jtl: Acta Oncologica issn: 0284186X maglogo: N pubinfo: dt: Mar2009 vid: 48 iid: 2 pid: 59195 pub: Medical Journals Sweden AB artinfo: ui: 105644683 105644683 2010185971 10.1080/02841860802251559 NLM18752085 105644683 ppf: 233 ppct: 5 formats: tig: atl: The feasibility of using Pareto fronts for comparison of treatment planning systems and delivery techniques. aug: au: Ottosson RO Engström PE Sjöström D Behrens CF Karlsson A Knöös T Ceberg C affil: Department of Oncology (R), Division of Radiophysics (51AA), Copenhagen University Hospital, Herlev, Denmark. riolot01@heh.regionh.dk sug: subj: Dosage Calculation Dosimetry Head and Neck Neoplasms Therapy Prostatic Neoplasms Therapy Radiotherapy Denmark Equipment and Supplies Sweden Human ab: Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitute the Pareto front. The Pareto concept applies well to the inverse planning process, which involves inherently contradictory objectives, high and uniform target dose on one hand, and sparing of surrounding tissue and nearby organs at risk (OAR) on the other. Due to the specific characteristics of a treatment planning system (TPS), treatment strategy or delivery technique, Pareto fronts for a given case are likely to differ. The aim of this study was to investigate the feasibility of using Pareto fronts as a comparative tool for TPSs, treatment strategies and delivery techniques. In order to sample Pareto fronts, multiple treatment plans with varying target conformity and dose sparing of OAR were created for a number of prostate and head & neck IMRT cases. The DVHs of each plan were evaluated with respect to target coverage and dose to relevant OAR. Pareto fronts were successfully created for all studied cases. The results did indeed follow the definition of the Pareto concept, i.e. dose sparing of the OAR could not be improved without target coverage being impaired or vice versa. Furthermore, various treatment techniques resulted in distinguished and well separated Pareto fronts. Pareto fronts may be used to evaluate a number of parameters within radiotherapy. Examples are TPS optimization algorithms, the variation between accelerators or delivery techniques and the degradation of a plan during the treatment planning process. The issue of designing a model for unbiased comparison of parameters with such large inherent discrepancies, e.g. different TPSs, is problematic and should be carefully considered. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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