Radiofrequency ablation of lung metastases: factors influencing success.

This paper analyses the factors associated with successful radiofrequency ablation (RFA) of lung metastases. The study group comprised 37 patients [19 female, mean age 61 (34-83)] with 72 metastases who had follow-up CT scans available for analysis and for those with no recurrence >6 months follow-u...

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Publicado en:European Radiology Vol. 18; no. 4; pp. 672 - 678
Autores principales: Gillams AR, Lees WR, Gillams, Alice R, Lees, William R
Formato: research Journal Article
Publicado: Springer Nature Apr2008
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Radiofrequency ablation of lung metastases: factors influencing success.
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          Gillams AR
          Lees WR
          Gillams, Alice R
          Lees, William R
        affil: Department of Medical Imaging, University College Hospital, London, UK
      sug:
        subj:
          Catheter Ablation
          Lung Neoplasms Surgery
          Adult
          Aged
          Aged, 80 and Over
          Chi Square Test
          Female
          Lung Neoplasms Radiography
          Lung Neoplasms
          Male
          Middle Age
          Neoplasm Recurrence, Local
          Tomography, X-Ray Computed
          Treatment Outcomes
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: This paper analyses the factors associated with successful radiofrequency ablation (RFA) of lung metastases. The study group comprised 37 patients [19 female, mean age 61 (34-83)] with 72 metastases who had follow-up CT scans available for analysis and for those with no recurrence >6 months follow-up. Internally cooled electrodes were used in 64 and expandable electrodes in 8. The tumour size and location, electrode type, number of ablations, duration of ablation, year of treatment and tumour contact with vessels larger than 3 mm were recorded. The mean tumour diameter was 1.8 cm (0.4-6.6 cm). Mean follow-up in those without recurrence was 13.1 months (6-48). Recurrence was common in larger tumours, occurring in 7/7 (100%) tumours >3.5 cm compared with 18/65 (28%) < or = 3.5 cm (P < 0.01). Recurrence occurred in 14/24 (58%) tumours in direct contact with large vessels compared with 11/48 (23%) of the remainder (P = 0.04). On multivariate analysis, size was the dominant feature (P = 0.013); vessel contact and peripheral location did not reach significance (P = 0.056 and 0.054 respectively). Peripheral tumours less than 3.5 cm with no large vessel contact are the optimal tumours for RFA.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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