Computational toxicology of chloroform: reverse dosimetry using Bayesian inference, Markov chain Monte Carlo simulation, and human biomonitoring data.

BACKGROUND: One problem of interpreting population-based biomonitoring data is the reconstruction of corresponding external exposure in cases where no such data are available. OBJECTIVES: We demonstrate the use of a computational framework that integrates physiologically based pharmacokinetic (PBPK)...

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Bibliographic Details
Published in:Environmental Health Perspectives Vol. 116; no. 8; pp. 1040 - 1047
Main Authors: Lyons MA, Yang RSH, Mayeno AN, Reisfeld B
Format: research Journal Article
Published: National Institute of Environmental Health Sciences Aug2008
Online Access:View this record in EBSCOhost