Stem-cells: prospects for treating dementia.
Stem cells have the capacity to generate multiple types of differentiated cells (multipotency) and undergo cell divisions in which at least one of the daughter cells maintains stem cell potentialIn the healthy adult brain, endogenous neural stem cells replace neurons in the hippocampus and olfactory...
| Publicado en: | British Journal of Neuroscience Nursing Vol. 4; no. 5; pp. 220 - 223 |
|---|---|
| Autores principales: | , , , |
| Formato: | glossary tables/charts Journal Article |
| Publicado: |
Mark Allen Holdings Limited
May2008
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105651286&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105651286 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17470307 1VOU jtl: British Journal of Neuroscience Nursing issn: 17470307 maglogo: N pubinfo: dt: May2008 vid: 4 iid: 5 pid: 11383 pub: Mark Allen Holdings Limited artinfo: ui: 105651286 2009991607 10.12968/bjnn.2008.4.5.29320 105651286 ppf: 220 ppct: 3 formats: fmt: @attributes: type: P tig: atl: Stem-cells: prospects for treating dementia. aug: au: Ekonomou A Cedar SH Ballard CG Minger SL affil: Research Fellow, Stem Cell Biology Laboratory and Translational Neuroscience Group, London Southbank University sug: subj: Alzheimer's Disease Surgery Brain Physiology Stem Cells Transplantation Cell Physiology Information Resources Tissue Transplantation Ethical Issues Treatment Outcomes World Wide Web ab: Stem cells have the capacity to generate multiple types of differentiated cells (multipotency) and undergo cell divisions in which at least one of the daughter cells maintains stem cell potentialIn the healthy adult brain, endogenous neural stem cells replace neurons in the hippocampus and olfactory bulbAdult neural stem cells can be isolated in the hippocampus and cultured ex vivo for extended periods with potential to differentiate them into neurons, astrocytes or oligodendrocytesIt is hypothesized that mental deterioration in Alzheimer's disease could be slowed and possibly reversed if neurons lost in the progression of the disease could be replaced using stem-cell therapyThe opportunity to enhance endogenous adult neural stem cells' proliferation, migration and differentiation into neurons will have great therapeutic potential for neurodegenerative diseases such as Alzheimer's disease pubtype: Academic Journal doctype: glossary tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|