Role of epigenetics in mental disorders.

The purpose of this paper was to selectively review the literature on the role of epigenetics in mental illnesses. Aberrant epigenetic regulation has been clearly implicated in the aetiology of some human illnesses. In recent years a growing body of evidence has highlighted the possibility that epig...

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Publicado en:Australian & New Zealand Journal of Psychiatry Vol. 42; no. 2; pp. 97 - 108
Autores principales: Stuffrein-Roberts S, Joyce PR, Kennedy MA
Formato: Journal Article
Publicado: Sage Publications Inc. Feb2008
Acceso en línea:Ver este registro en EBSCOhost
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          Stuffrein-Roberts S
          Joyce PR
          Kennedy MA
        affil: Department of Pathology, University of Otago, Christchurch, New Zealand. stuffres@hotmail.com
      sug:
        subj:
          Genes Physiology
          Mental Disorders
          Chromosomes Physiology
          Chromosomes
          Depression Drug Therapy
          Depression Metabolism
          DNA Physiology
          DNA
          Genes
          Genetics
          Heterocyclic Compounds Metabolism
          Mental Disorders Drug Therapy
          Mental Disorders Physiopathology
          Monoamine Oxidase Inhibitors Pharmacokinetics
          Monoamine Oxidase Inhibitors Therapeutic Use
      ab: The purpose of this paper was to selectively review the literature on the role of epigenetics in mental illnesses. Aberrant epigenetic regulation has been clearly implicated in the aetiology of some human illnesses. In recent years a growing body of evidence has highlighted the possibility that epigenetics may also play a key role in the origins and expression of mental disorders. Epigenetic phenomena may help explain some of the complexity of mental illnesses and provide a basis for discovering novel pharmacological targets to treat these disorders.
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    language: English
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