Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure.

BACKGROUND: Human exposure to brevetoxins produced by the red tide organism, Karenia brevis, is an increasing public health concern. Using in vitro exposure of rat liver cells to brevetoxin B (PbTx-2), the primary toxin product of K. brevis, we previously showed that it formed C(27,28)-epoxy breveto...

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Bibliographic Details
Published in:Environmental Health Perspectives Vol. 116; no. 7; pp. 930 - 937
Main Authors: Radwan FFY, Ramsdell JS
Format: research Journal Article
Published: National Institute of Environmental Health Sciences Jul2008
Online Access:View this record in EBSCOhost