The effects of exercise training on quality of life in HAART-treated HIV-positive Rwandan subjects with body fat redistribution.

Objective: Our objective was to examine the effects of exercise training (EXS) on quality of life (QoL) in highly active antiretroviral therapy (HAART)-treated HIV-positive (HIV+) subjects with body fat redistribution (BFR) in Rwanda.Methods: The effects of a randomised controlled trial of EXS on Qo...

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Publicado en:Quality of Life Research Vol. 17; no. 3; pp. 377 - 386
Autores principales: Mutimura E, Stewart A, Crowther NJ, Yarasheski KE, Cade WT, Mutimura, Eugene, Stewart, Aimee, Crowther, Nigel J, Yarasheski, Kevin E, Cade, W Todd
Formato: clinical trial research Journal Article
Publicado: Springer Nature Apr2008
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2008
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      pub: Springer Nature
      place: New York, New York
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        atl: The effects of exercise training on quality of life in HAART-treated HIV-positive Rwandan subjects with body fat redistribution.
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          Mutimura E
          Stewart A
          Crowther NJ
          Yarasheski KE
          Cade WT
          Mutimura, Eugene
          Stewart, Aimee
          Crowther, Nigel J
          Yarasheski, Kevin E
          Cade, W Todd
        affil: Faculty of Allied Health Sciences, Kigali Health Institute, PO Box 3286, Kigali, Rwanda
      sug:
        subj:
          Adipose Tissue
          Antiretroviral Therapy, Highly Active
          Antiviral Agents Therapeutic Use
          Anti-HIV Agents
          Quality of Life
          Therapeutic Exercise
          Adult
          Body Composition
          Body Weights and Measures
          Clinical Trials
          Exercise
          Female
          Health Status
          Male
          Psychological Tests
          Psychometrics
          Rwanda
          Human
          Adult: 19-44 years
          Female
          Male
      ab: Objective: Our objective was to examine the effects of exercise training (EXS) on quality of life (QoL) in highly active antiretroviral therapy (HAART)-treated HIV-positive (HIV+) subjects with body fat redistribution (BFR) in Rwanda.Methods: The effects of a randomised controlled trial of EXS on QoL were measured using World Health Organisation Quality of Life (WHOQOL)-BREF in HIV+ subjects with BFR randomised to EXS (n = 50; BFR + EXS) or no exercise training (n = 50; BFR + noEXS).Results: At 6 months, scores on the psychological [1.3 (0.3) vs. 0.5 (0.1); P < 0.0001], independence [0.6 (0.1) vs. 0.0 (0.0); P < 0.0001], social relationships [0.6 (0.2) vs. 0.0 (0.0); P < 0.0001] and HIV HAART-specific QoL domains [1.4 (0.2) vs. -0.1 (0.2); P < 0.0001] improved more in BFR + EXS than BFR + noEXS group, respectively. Self-esteem [1.3 (0.8) vs. 0.1 (0.6); P < 0.001], body image [1.5 (0.6) vs. 0.0 (0.5); P < 0.001] and emotional stress [1.6 (0.7) vs. 0.2 (0.5); P < 0.001] improved more in the BFR + EXS group than BFR + noEXS group, respectively. Psychological [1.5 (0.2) vs. 1.1 (0.3); P < 0.0001], social relationship [0.8 (0.2) vs. 0.4 (0.2); P < 0.0001], and HIV HAART-specific well-being [1.8 (0.2) vs. 1.0 (0.0); P < 0.0001] improved more in BFR + EXS female than male subjects.Conclusions: Exercise training improved several components of QoL in HAART-treated HIV+ African subjects with BFR. Exercise training is an inexpensive and efficacious strategy for improving QoL in HIV+ African subjects, which may improve HAART adherence and treatment initiatives in resource-limited areas of sub-Saharan Africa.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        Journal Article
      ougenre: Article
    language: English
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