Endoscopic tumor ablation for laryngotracheal intraluminal invasion secondary to advanced thyroid cancer.
Conclusions. Endoscopic tumor ablation is a valuable option for inoperable postoperative laryngotracheal intraluminal invasion of well-differentiated thyroid carcinoma (DTC). Objectives. To investigate whether DTC invasion to the laryngotracheal mucosa can be controlled by 'simple' tumor ablation co...
| Publicado en: | Acta Oto-Laryngologica Vol. 128; no. 7; pp. 799 - 808 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jul2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105704616&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105704616 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00016489 B6D jtl: Acta Oto-Laryngologica issn: 00016489 maglogo: Y pubinfo: dt: Jul2008 vid: 128 iid: 7 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 105704616 2009961512 10.1080/00016480701714285 NLM18568524 105704616 ppf: 799 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Endoscopic tumor ablation for laryngotracheal intraluminal invasion secondary to advanced thyroid cancer. aug: au: Tsutsui H Usuda J Kubota M Yamada M Suzuki A Shibuya H Miyajima K Tanaka K Sugino K Ito K Kato H affil: Department of Surgery I, Tokyo Medical University, Tokyo sug: subj: Endoscopy Laryngeal Neoplasms Surgery Laser Therapy Neoplasm Metastasis Surgery Thyroid Neoplasms Complications Aged Aged, 80 and Over Descriptive Statistics ENT Endoscopes Female Japan Kaplan-Meier Estimator Male Middle Age Record Review Retrospective Design Human Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Conclusions. Endoscopic tumor ablation is a valuable option for inoperable postoperative laryngotracheal intraluminal invasion of well-differentiated thyroid carcinoma (DTC). Objectives. To investigate whether DTC invasion to the laryngotracheal mucosa can be controlled by 'simple' tumor ablation considering its relatively slow-growing nature. Patients and methods. Twenty-two consecutive patients underwent endoscopic tumor ablation caused by DTC for local control of intraluminal lesions with no significant extrinsic laryngotracheal compression in symptomatic or asymptomatic patients in whom radical operations were contraindicated. Debulking by Nd:YAG laser was followed by electrocoagulation and microwave coagulation for the residual tumor base. Results. The critical complication, post-treatment supraglottic stenosis, was managed by prophylactic minitracheotomy. During the follow-up period of up to 125 months, 6 of 22 patients died (median survival 50 months), mainly of lung metastases, but all had a patent airway at death. Post-surgical extraluminal lesion growth is indolent and since relapse of the intraluminal lesion is the main cause of symptoms, satisfactory local control could be obtained by re-ablation of the mucosal lesion every few years. Lesions requiring retreatment within 1 year after initial treatment usually have high-grade malignancy, causing extrinsic compression, and prognosis is unfavorable. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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