High prevalence of isovolumic relaxation flow in healthy subjects.
Background: Inhomogenous left ventricular activation-inactivation has been suggested to play a role in the genesis of segmental early relaxation and in turn of isovolumic relaxation flow (IRF). The spatial distribution of conduction system in the left ventricle leads to heterogenous activation seque...
| Publicado en: | Echocardiography Vol. 21; no. 7; pp. 581 - 586 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2004
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105716551&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105716551 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Oct2004 vid: 21 iid: 7 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 105716551 2009399985 10.1111/j.0742-2822.2004.03112.x NLM15488084 105716551 ppf: 581 ppct: 5 formats: fmt: @attributes: type: P tig: atl: High prevalence of isovolumic relaxation flow in healthy subjects. aug: au: Voon WC Huang CH Lin TH Lai WT Sheu SH sug: subj: Vasodilation Physiology Adolescence Adult Age Factors Aged Aged, 80 and Over Blood Flow Velocity Physiology Echocardiography, Doppler, Pulsed Electrocardiography Female Heart Atrium Ultrasonography Heart Rate Physiology Heart Ventricle Physiology Heart Ventricle Ultrasonography Male Middle Age Myocardial Contraction Physiology Prevalence Prospective Studies Reference Values Human Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Background: Inhomogenous left ventricular activation-inactivation has been suggested to play a role in the genesis of segmental early relaxation and in turn of isovolumic relaxation flow (IRF). The spatial distribution of conduction system in the left ventricle leads to heterogenous activation sequence even in healthy subjects. This study was conducted to evaluate our hypothesis that IRF should be ubiquitous in healthy subjects. Methods: This prospective study included 126 healthy subjects (aged 15-81 years) free of acute or chronic illness by history and physical examination. No significant abnormality appeared in the resting 12-lead electrocardiogram or transthoracic echocardiogram. With the pulsed-wave Doppler echocardiography, the sample volume was placed at the mid-ventricle to detect the IRF. Results: An apically directed IRF, with the velocity 17-101 cm/sec and the duration 57-145 ms, could be detected in all the study subjects. There was no inter-sex difference in such characteristics of IRF. However, its duration and velocity got longer and higher with aging. The fractional shortening of the left ventricle and the interventricular septal thickness were stepwisely selected as the determinants of the IRF velocity, and the transmitral E-to-A wave velocity ratio, the left ventricular inflow propagation velocity, and the interventricular septal thickness as the determinants of the IRF duration. Conclusions: IRF is ubiquitous in healthy subjects. Both the duration and the velocity of IRF present an aging trend and may be mainly related to left ventricular diastolic and systolic performance, respectively.(ECHOCARDIOGRAPHY, Volume 21, October 2004) pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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