Application of an electrocardiographic inverse solution to localize ischemia during coronary angioplasty.

This study demonstrates the utility of an electrocardiographic inverse solution, coupled with body surface potential mapping (BSPM), In localizing acute ischemia in patients undergoing percutaneous transluminal coronary angioplasty (PTCA). PTCA balloon inflations produce complete occlusion and acute...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 6; no. 1; pp. 2 - 19
Autores principales: MacLeod RS, Gardner M, Miller RM, Horácek BM
Formato: Journal Article
Publicado: Wiley-Blackwell Jan1995
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan1995
      vid: 6
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Application of an electrocardiographic inverse solution to localize ischemia during coronary angioplasty.
      aug:
        au:
          MacLeod RS
          Gardner M
          Miller RM
          Horácek BM
      sug:
        subj:
          Angioplasty, Transluminal, Percutaneous Coronary Adverse Effects
          Electrocardiography Methods
          Myocardial Ischemia Diagnosis
          Computer Simulation
          Models, Theoretical
          Myocardial Ischemia Etiology
      ab: This study demonstrates the utility of an electrocardiographic inverse solution, coupled with body surface potential mapping (BSPM), In localizing acute ischemia in patients undergoing percutaneous transluminal coronary angioplasty (PTCA). PTCA balloon inflations produce complete occlusion and acute transient ischemia, which can be detected electrocardiographically with BSPM. Comparisons between maps recorded both during and before the inflation of the PTCA balloon allow patient- and artery-specific characterizations of the resulting Ischemia. Knowledge of the patient's coronary anatomy and the location of the occlusion site by coronary angiography permit an estimation based on cardiac hemodynamics of the region of myocardium most likely to suffer from PTCA-induced ischemia. Electrocardiographic inverse solutions provide a means of predicting cardiac potentials from body surface maps. In this study, we describe an inverse solution we have developed to localize the transient ischemia produced by PTCA. To validate the procedure, we compared the locations of predicted ischemia in seven patients with a qualitative estimate of the perfusion region based on fluoroscopic examination of each patient's coronary anatomy and PTCA balloon location. In each case, the region of ischemia predicted by the model included the perfusion zone determined fluoroscopically. These results suggest that electrical changes induced by acute ischemia can be localized with an electrocardiographic inverse solution.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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