Initial clinical experience with a fully automatic in-hospital external cardioverter defibrillator.

Sudden cardiac death due to ventricular tachyarrhythmia remains a significant problem in the in-hospital setting. Although the probability of survival is closely correlated with the rapidity of a response by qualified personnel, response times can be prolonged, even in specialized care units. In an...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 22; no. 11; pp. 1648 - 1656
Autores principales: Mattioni TA, Nademanee K, Brodsky M, Fisher J, Riggio D, Allen B, Welch S, Ybarra RA, Lin D, Dean E
Formato: clinical trial research Journal Article
Publicado: Wiley-Blackwell Nov1999
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Initial clinical experience with a fully automatic in-hospital external cardioverter defibrillator.
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        au:
          Mattioni TA
          Nademanee K
          Brodsky M
          Fisher J
          Riggio D
          Allen B
          Welch S
          Ybarra RA
          Lin D
          Dean E
      sug:
        subj:
          Cardioversion Equipment and Supplies
          Heart Arrest Therapy
          Tachycardia, Ventricular Therapy
          Ventricular Fibrillation Therapy
          Adult
          Clinical Trials
          Coronary Care Units
          Electrocardiography, Ambulatory Equipment and Supplies
          Electrodes
          Equipment Design
          Equipment Safety
          Female
          Heart Arrest Etiology
          Male
          Middle Age
          Signal Processing, Computer Assisted Equipment and Supplies
          Tachycardia, Ventricular Etiology
          Treatment Outcomes
          Ventricular Fibrillation Etiology
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Sudden cardiac death due to ventricular tachyarrhythmia remains a significant problem in the in-hospital setting. Although the probability of survival is closely correlated with the rapidity of a response by qualified personnel, response times can be prolonged, even in specialized care units. In an effort to decrease response time, a fully automatic external cardioverter defibrillator was recently devised. This device was evaluated in the in-hospital setting to assess safety and efficacy. A total of 79 patients were studied in a multicenter trial. Patients were monitored with fully functional devices in the electrophysiology laboratory (51 patients) and in the cardiac care unit (28 patients). Performance of the device was assessed by comparing automatic responses to any sustained change in cardiac rhythm, either spontaneous or induced, to a retrospective review of stored ECG data and programmed parameters. During a total duration of 964 hours of monitoring, there were 99 episodes of sustained tachycardia. Therapy was appropriately delivered or advised in all episodes. Therapy was advised in one episode of supraventricular tachycardia. There were no episodes of inappropriate therapy delivery. There were no complications or adverse events. The device performed with a sensitivity of 100% and specificity of 98.8% with an average response time of 22 seconds. In conclusion, this automatic external defibrillator was safe, effective, and functioned as designed. Significant improvement in response time to life-threatening ventricular tachyarrhythmia in the in-hospital setting would be expected if this technology was widely adopted.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        Journal Article
      ougenre: Article
    language: English
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