Genesis of sigmoidal dose-response curve during defibrillation by random shock: a theoretical model based on experimental evidence for a vulnerable window during ventricular fibrillation.

The sigmoidal dose-response curve (percent success vs shock energy) suggests a probabilistic nature of defibrillation. The mechanism is still largely unknown, however, random variation in the excitable state during ventricular fibrillation (VF) is suspected. A canine defibrillation study was designe...

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Bibliographic Details
Published in:Pacing & Clinical Electrophysiology Vol. 13; no. 10; pp. 1326 - 1343
Main Authors: Hsia PW, Mahmud R
Format: Journal Article
Published: Wiley-Blackwell Oct1990
Online Access:View this record in EBSCOhost