False-negative results after stereotactically guided vacuum biopsy.

The purpose of this study was to determine the false negative rate of stereotactically guided vacuum biopsy (VB). Data of patients with benign lesions in VB were evaluated retrospectively during a median follow-up period of 21 months. A total of 404 VB were considered benign and representative and w...

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Publicado en:European Radiology Vol. 18; no. 1; pp. 177 - 183
Autores principales: Peter D, Grünhagen J, Wenke R, Schäfer FK, Schreer I, Peter, D, Grünhagen, J, Wenke, R, Schäfer, F K W, Schreer, I
Formato: research Journal Article
Publicado: Springer Nature Jan2008
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-007-0707-x
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        atl: False-negative results after stereotactically guided vacuum biopsy.
      aug:
        au:
          Peter D
          Grünhagen J
          Wenke R
          Schäfer FK
          Schreer I
          Peter, D
          Grünhagen, J
          Wenke, R
          Schäfer, F K W
          Schreer, I
        affil: Breast Center, Department of Radiology, University Schleswig-Holstein, Campus Kiel, Michaelisstr. 16, 24105 Kiel, Germany
      sug:
        subj:
          Biopsy Methods
          Breast Neoplasms Pathology
          Stereotaxic Techniques
          Adult
          Aged
          Aged, 80 and Over
          Breast Neoplasms Radiography
          Diagnosis, Differential
          False Negative Results
          Mammography
          Middle Age
          Retrospective Design
          Vacuum
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
      ab: The purpose of this study was to determine the false negative rate of stereotactically guided vacuum biopsy (VB). Data of patients with benign lesions in VB were evaluated retrospectively during a median follow-up period of 21 months. A total of 404 VB were considered benign and representative and were recommended for follow-up. Of these 404 lesions, 195 were completely removed radiologically. Follow-up data were available for 354/404 patients (87.6%), with intervals ranging from 3 to 66 months (median 21, mean 22.4). Reintervention or surgery was necessary in 13/354 (3.7%) cases. Of these cases, 5/354 (1.4%) turned out to be false negatives. Four of these cases showed large areas of microcalcifications or several clusters, and only partial removal was possible due to the size of the lesions. Although VB is an accurate procedure for diagnosing nonpalpable breast lesions with a low cancer miss rate, we consider the exclusion of malignancy in cases of disseminated microcalcifications or several clusters as a limitation. The radiologic-pathologic correlation in these cases is a challenge, particularly in terms of the residuals. Strict follow-up of benign lesions is essential to avoid delayed cancer diagnosis.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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