Deoxycholic acid can induce apoptosis in the human colon cancer cell line HCT116 in the absence of Bax.
In the human colon cancer cells HCT116, deoxycholic acid (DCA) induces apoptosis via the mitochondrial pathway by triggering the release of mitochondrial factors such as cytochrome c. To elucidate if Bax, a proapoptotic member of the Bcl-2 family known to trigger cytochrome c release in response to...
| Publicado en: | Nutrition & Cancer Vol. 60; no. 1; pp. 91 - 97 |
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| Autores principales: | , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
2008
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| Acceso en línea: | Ver este registro en EBSCOhost |