Work area measurements as predictors of personal exposure to endotoxin and cotton dust in the cotton textile industry.

Objectives: To determine if work area measurements of endotoxin and/or cotton dust obtained from the vertical elutriator (VE) can be used to predict levels of personal endotoxin exposure as measured by the Institute of Occupational Medicine (IOM) inhalable dust sampler in the cotton textile industry...

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Publicado en:Annals of Occupational Hygiene Vol. 52; no. 1; pp. 45 - 55
Autores principales: Mehta AJ, Wang XR, Eisen EA, Dai HL, Astrakianakis G, Seixas N, Camp J, Checkoway H, Christiani DC
Formato: research Journal Article
Publicado: Oxford University Press / USA Jan2008
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Work area measurements as predictors of personal exposure to endotoxin and cotton dust in the cotton textile industry.
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        au:
          Mehta AJ
          Wang XR
          Eisen EA
          Dai HL
          Astrakianakis G
          Seixas N
          Camp J
          Checkoway H
          Christiani DC
        affil: Department of Environmental Health, Environmental and Occupational Medicine and Epidemiology Program, Harvard School of Public Health, Boston, MA, USA.
      sug:
        subj:
          Air Pollutants, Occupational Analysis
          Environmental Monitoring Methods
          Occupational Exposure Analysis
          Textile Industry
          Textiles
          Dust Analysis
          Endotoxins Analysis
          Human
      ab: Objectives: To determine if work area measurements of endotoxin and/or cotton dust obtained from the vertical elutriator (VE) can be used to predict levels of personal endotoxin exposure as measured by the Institute of Occupational Medicine (IOM) inhalable dust sampler in the cotton textile industry. Methods: Fifty-six work area cotton dust samples were collected from 14 areas and 82 personal cotton dust samples were collected from 41 workers in three textile mills (Mills A, B and C) in Shanghai, China. Cotton dust concentrations were determined gravimetrically from sample filters, of which endotoxin concentrations were determined using a kinetic chromogenic modification of the limulus amoebocyte lysate assay. Linear regression models were used to determine the association between log IOM personal endotoxin concentration and log VE area endotoxin concentration. Results: Median cotton dust and endotoxin concentrations measured from VE area samples in the three mills were 0.36 mg m−3 and 1280.76 endotoxin units per cubic meter (EU m−3), respectively, compared to 1.74 mg m−3 and 2226.83 EU m−3 from IOM personal samples. Excluding samples from weaving processes, we observed linear associations between VE area measures of endotoxin and IOM personal endotoxin concentrations; VE area concentration of endotoxin explained 83 and 89% of the total variation in IOM personal endotoxin concentration for Mills A and B, respectively (Mill A: R2 = 0.83, P R2 = 0.89, P < 0.0001). Although area measures of cotton dust was also a significant predictor of person endotoxin, the model explained less of the variance in personal endotoxin measurements. Conclusions: Specific to the conditions of the textile mills investigated in this study, work area measurements of endotoxin, but not cotton dust, may be reasonable proxies for personal levels, at least for rank-ordering exposures.
      pubtype: Academic Journal
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        Journal Article
      ougenre: Article
    language: English
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