Use of cell viability assay data improves the prediction accuracy of conventional quantitative structure-activity relationship models of animal carcinogenicity.

BACKGROUND: To develop efficient approaches for rapid evaluation of chemical toxicity and human health risk of environmental compounds, the National Toxicology Program (NTP) in collaboration with the National Center for Chemical Genomics has initiated a project on high-throughput screening (HTS) of...

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Bibliographic Details
Published in:Environmental Health Perspectives Vol. 116; no. 4; pp. 506 - 514
Main Authors: Zhu H, Rusyn I, Richard A, Tropsha A
Format: equations & formulas research tables/charts Journal Article
Published: National Institute of Environmental Health Sciences Apr2008
Online Access:View this record in EBSCOhost