Mechanism of selenium-induced inhibition of arsenic-enhanced UVR carcinogenesis in mice.

BACKGROUND: Hairless mice that ingested arsenite in drinking water exhibited more than a 5-fold enhancement of ultraviolet radiation (UVR) carcinogenesis, whereas arsenite alone was carcinogenically inactive. Dietary organoselenium blocked the cancer enhancement effect of arsenic but not cancer indu...

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Bibliographic Details
Published in:Environmental Health Perspectives Vol. 116; no. 6; pp. 703 - 709
Main Authors: Burns FJ, Rossman T, Vega K, Uddin A, Vogt S, Lai B, Reeder RJ
Format: pictorial research tables/charts Journal Article
Published: National Institute of Environmental Health Sciences Jun2008
Online Access:View this record in EBSCOhost