Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice.

Objective: The aim of our study was to explore the immunomodulatory activity of soluble immunoglobulin (Ig)-like transcript (ILT) 3-Fc in pancreatic islet transplantation and to determine its mechanism of action.Research Design and Methods: NOD/SCID mice in which diabetes was induced by streptozotoc...

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Detalles Bibliográficos
Publicado en:Diabetes Vol. 57; no. 7; pp. 1878 - 1887
Autores principales: Vlad G, D'Agati VD, Zhang QY, Liu Z, Ho EK, Mohanakumar T, Hardy MA, Cortesini R, Suciu-Foca N, Vlad, George, D'Agati, Vivette D, Zhang, Qing-Yin, Liu, Zhuoru, Ho, Eric K, Mohanakumar, Thalachallour, Hardy, Mark A, Cortesini, Raffaello, Suciu-Foca, Nicole
Formato: research Journal Article
Publicado: American Diabetes Association Jul2008
Acceso en línea:Ver este registro en EBSCOhost