Immunity to varicella zoster virus among young adults: a decline prior to widespread uptake of varicella vaccines.

The epidemiology of chickenpox in Israel is changing, mainly due to the increasing - but not universal - uptake of varicella vaccine. We conducted a seroprevalence study of varicella zoster virus (VZV) antibodies among 536 Israeli military recruits 18 years of age, on the basis of a representative s...

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Publicado en:Infection Vol. 36; no. 2; pp. 130 - 135
Autores principales: Grotto I, Balicer RD, Smetana Z, Davidovitch N, Bar-Zeev Y, Mendelson E, Zarka S, Huerta M
Formato: research tables/charts Journal Article
Publicado: Springer Nature Apr2008
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Immunity to varicella zoster virus among young adults: a decline prior to widespread uptake of varicella vaccines.
      aug:
        au:
          Grotto I
          Balicer RD
          Smetana Z
          Davidovitch N
          Bar-Zeev Y
          Mendelson E
          Zarka S
          Huerta M
        affil: Epidemiology Department, Faculty of Health Sciences, Ben-Gurion University of the Negev, PO Box 653, Beer-Sheva 84105, Israel; grotto@bgu.ac.il
      sug:
        subj:
          Chickenpox Immunology
          Disease Susceptibility In Adolescence
          Adolescence
          Chi Square Test
          Confidence Intervals
          Data Analysis Software
          Descriptive Statistics
          Disease Susceptibility Trends
          Female
          Immunoassay
          Immunoglobulins Blood
          Israel
          Male
          Seroprevalence Studies
          T-Tests
          Human
          Adolescent: 13-18 years
          Female
          Male
      ab: The epidemiology of chickenpox in Israel is changing, mainly due to the increasing - but not universal - uptake of varicella vaccine. We conducted a seroprevalence study of varicella zoster virus (VZV) antibodies among 536 Israeli military recruits 18 years of age, on the basis of a representative sample of sera collected in 2003. The overall seroprevalence rate was 94.6%, which was significantly lower than that observed in a similar population in 1992 (98.4%, p < 0.001). The rate was lower among subjects whose fathers had less than 12 years of schooling (89.8%, p = 0.033). No statistically significant differences were observed when data were stratified by sex, subject's level of education, or origin. This decline in the level of immunity must be considered when determining pre- and post-exposure vaccination policy among young adults in crowded environments.
      pubtype: Academic Journal
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        tables/charts
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    language: English
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