The effect on heart rate of combining single-dose fingolimod with steady-state atenolol or diltiazem in healthy subjects.
OBJECTIVE: The sphingosine-1-phosphate receptor modulator fingolimod (FTY720) is known to elicit a negative chronotropic effect at treatment initiation that attenuates over time with continued dosing. The authors determined the effect of combining a single dose of fingolimod with steady-state atenol...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 64; no. 5; pp. 457 - 464 |
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| Autores principales: | , , , , , , |
| Formato: | clinical trial research Journal Article |
| Publicado: |
Springer Nature
May2008
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| Acceso en línea: | Ver este registro en EBSCOhost |