Novel ultrasound contrast agent dilution method for the assessment of ventricular ejection fraction.
AIMS: Left ventricular (LV) ejection fraction is an important determinant of prognosis in heart failure. We evaluated the accuracy of a novel algorithm for LV ejection fraction quantification based on indicator dilution curve (IDC) principles using ultrasound contrast as indicator, and compared the...
| Publicado en: | European Journal of Echocardiography Vol. 9; no. 4; pp. 489 - 494 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Oxford University Press / USA
Jul2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105803718&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105803718 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15252167 NYG jtl: European Journal of Echocardiography issn: 15252167 maglogo: N pubinfo: dt: Jul2008 vid: 9 iid: 4 pid: 622 pub: Oxford University Press / USA artinfo: ui: 105803718 2009980653 10.1016/j.euje.2007.07.007 NLM17905661 105803718 ppf: 489 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Novel ultrasound contrast agent dilution method for the assessment of ventricular ejection fraction. aug: au: Jansen A Mischi M Bracke F van Dantzig JM Peels K Lamfers E van Hemel N Korsten H affil: Department of Cardiology, Catharina Hospital, Michelangelolaan 2/P.O. Box 1350, 5602 ZA Eindhoven, The Netherlands. annemieke.jansen@cze.nl sug: subj: Cardiovascular System Physiology Contrast Media Heart Diseases Ultrasonography Phospholipids Diagnostic Use Stroke Volume Sulfur Compounds Diagnostic Use Aged Algorithms Echocardiography Female Male Middle Age Aged: 65+ years Middle Aged: 45-64 years Female Male ab: AIMS: Left ventricular (LV) ejection fraction is an important determinant of prognosis in heart failure. We evaluated the accuracy of a novel algorithm for LV ejection fraction quantification based on indicator dilution curve (IDC) principles using ultrasound contrast as indicator, and compared the results with contrast enhanced biplane LV ejection fraction assessment. Method A diluted ultrasound contrast bolus (SonoVue) was injected intravenously in 31 patients (19 male, age 65 +/- 11) with known or suspected heart disease. A total of 68 recordings were made. The developed algorithm used the left atrium and LV IDC for LV ejection fraction measurement. Biplane enhanced LV ejection fraction measurements with pure ultrasound contrast (SonoVue) were determined in multiple four- and two-chamber recordings as reference. RESULTS: The mean LV ejection fraction measured by biplane and IDC method was 33 +/- 17% and 35 +/- 18%, respectively. A correlation coefficient r = 0.93 was observed between the two methods. Bland-Altman analysis demonstrated a slight LV ejection fraction overestimation with IDC (mean 1.9 +/- 6.3%). CONCLUSION: A new fast method for LV ejection fraction assessment based on IDC principles is described and comparison with contrast enhanced biplane LV ejection fraction quantification shows accurate results. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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