The impact of aging on left ventricular longitudinal function in healthy subjects: a pulsed tissue Doppler study.
AIMS: To evaluate the influence of age on average values of pulsed tissue Doppler recorded at the septal and lateral mitral annulus in a population of healthy subjects and to propose reference values according to different age decades. METHODS AND RESULTS: Two hundred and forty-six healthy subjects...
| Publicado en: | European Journal of Echocardiography Vol. 9; no. 2; pp. 241 - 250 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
Mar2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105813986&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105813986 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15252167 NYG jtl: European Journal of Echocardiography issn: 15252167 maglogo: N pubinfo: dt: Mar2008 vid: 9 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 105813986 105813986 2009921069 NLM17586096 105813986 ppf: 241 ppct: 9 formats: fmt: @attributes: type: P tig: atl: The impact of aging on left ventricular longitudinal function in healthy subjects: a pulsed tissue Doppler study. aug: au: Innelli P Sanchez R Marra F Esposito R Galderisi M affil: Division of Cardioangiology with CCU, Department of Clinical and Experimental Medicine, Federico II University Hospital, Block 1, Via S. Pansini 5, 80131 Naples, Italy sug: subj: Aging Physiology Cardiovascular System Physiology Echocardiography, Doppler, Pulsed Ventricular Dysfunction, Left Ultrasonography Adolescence Adult Aged Aged, 80 and Over Child Data Analysis, Statistical Female Male Middle Age Reference Values Ventricular Dysfunction, Left Physiopathology Human Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Child: 6-12 years Middle Aged: 45-64 years Female Male ab: AIMS: To evaluate the influence of age on average values of pulsed tissue Doppler recorded at the septal and lateral mitral annulus in a population of healthy subjects and to propose reference values according to different age decades. METHODS AND RESULTS: Two hundred and forty-six healthy subjects (M/F = 160/86, mean age 40.9 years) underwent Doppler-echocardiography and pulsed tissue Doppler of the septal and lateral mitral annulus. S(m), E(m), A(m) peak velocities were measured at both the annular sides and average values obtained. The ratio of transmitral E peak velocity and average E(m) peak velocity (lateral E(m) + septal E(m)/2) was calculated as an index of left ventricular filling pressure. The population was divided into seven age decades: 10-19, 20-29, 30-39, 40-49, 50-59, 60-69 years and >70 years. E(m) was progressively reduced and A(m) increased with increasing age at both the annular sides as well as average values. S(m) reduction with advancing age was significant only at the lateral mitral annulus and as average values. Average E/E(m) ratio was particularly higher in the last three age decades. By multilinear regression analyses, age was the main independent predictor of average E(m), A(m) and E/E(m) ratio, while heart rate was the most important contributor to average S(m), with the additional contribution of age. CONCLUSIONS: Aging shows an independent impact on average tissue Doppler indexes of septal and lateral mitral annulus in normal subjects. Our data also provide reference values of tissue Doppler average variables for age decades. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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