Molecular typing of Streptococcus pyogenes from remote Aboriginal communities where rheumatic fever is common and pyoderma is the predominant streptococcal infection.
SUMMARYAboriginal Australians in remote communities have high rates of rheumatic heart disease (RHD); yet pharyngitis is reportedly rare whilst pyoderma is common. Some strains of group A streptococci (GAS) have preference for the throat and others for the skin depending on M protein type. A study i...
| Publicado en: | Epidemiology & Infection Vol. 135; no. 8; pp. 1398 - 1406 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Cambridge University Press
Nov2007
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105825319&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105825319 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09502688 2S0 jtl: Epidemiology & Infection issn: 09502688 maglogo: N pubinfo: dt: Nov2007 vid: 135 iid: 8 pid: 15979 pub: Cambridge University Press artinfo: ui: 105825319 105825319 2009726376 10.1017/s0950268807008023 NLM17306049 105825319 ppf: 1398 ppct: 8 formats: tig: atl: Molecular typing of Streptococcus pyogenes from remote Aboriginal communities where rheumatic fever is common and pyoderma is the predominant streptococcal infection. aug: au: McDonald MI Towers RJ Fagan P Carapetis JR Currie BJ affil: Department of Paediatrics, University of Melbourne and Murdoch Children's Research Institute, Melbourne, Victoria, Australia. sug: subj: Bacterial Typing Techniques Pyoderma Epidemiology Rheumatic Fever Epidemiology Streptococcal Infections Epidemiology Streptococcal Infections Microbiology Streptococcus Classification Antigens, Bacterial Australia Carrier Proteins Child DNA Female Genotype Male Membrane Proteins Pharynx Microbiology Pyoderma Microbiology Rheumatic Fever Microbiology Rural Population Sequence Analysis Skin Microbiology Streptococcus Child: 6-12 years Female Male ab: SUMMARYAboriginal Australians in remote communities have high rates of rheumatic heart disease (RHD); yet pharyngitis is reportedly rare whilst pyoderma is common. Some strains of group A streptococci (GAS) have preference for the throat and others for the skin depending on M protein type. A study in three remote communities provided 350 GAS isolates for emm sequence typing, 244 were also emm pattern typed. There was 100% correlation between emm sequence and pattern type. Patterns D and E (non-throat tropic) made up 71% of throat and 87% of skin isolates although patterns A-C (throat tropic) were more common in the throat than the skin (RR 2.3, 95% CI 1.4-3.8) whilst the opposite was found for pattern D (RR 2.2, 95% CI 1.7-3.0). Pattern E favoured the throat (RR 1.4, 95% CI 1.1-1.8). Where environmental factors predispose to skin infection, emm pattern types D and E prevail, whatever the recovery site. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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